Results 71 to 80 of about 3,999,813 (301)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

PERAN MANAJEMEN KELAS DALAM MEWUJUDKAN PEMBELAJARAN YANG KREATIF

open access: yesGuruku
This research aims to analyze the role of classroom management in creating creative learning at SDN Pemulutan Barat 3 Kamal Village. Using a qualitative-based descriptive approach, this research involves students and teachers as subjects, and data ...
Sinta Dwiyana, Ade Akhmad Saputra
doaj   +1 more source

Creative Industries Innovation Centre Case Study - creative territory.pdf

open access: yes, 2015
In 2011, the Creative Industries Innovation Centre worked with its industry partners to select 50 high potential creative enterprises from around the nation to participate in a series of business model workshops.
Creative Industries Innovation Centre
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Why do creative industries cluster? An analysis of the determinants of clustering of creative industries [PDF]

open access: yes
Creative industries tend to concentrate mainly around large- and medium-sized cities, forming creative local production systems. The text analyses the forces behind clustering of creative industries to provide the first empirical explanation of the ...
Rafael Boix   +2 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

THE FACETS OF CREATIVITY ECONOMY

open access: yesХабаршысы. Экономика сериясы, 2018
This paper discusses various aspects of so called «creative economy» and «creativity economy», two of many modern concepts characterizing the «new economy» based on knowledge, IC-technologies, creativity and innovation.
Dubina I.N.
doaj  

Effectiveness of Probing-prompting Learning Models with Scaffolding Strategy to Mathematic Creative Thinking Ability and Enthusiasm

open access: yesUnnes Journal of Mathematics Education, 2017
The purpose of this research was to know that the learning model ProbingPrompting with Scaffolding strategy effective on the mathematic creative thinking ability and enthusiasm.
Miftah Hafidz Alfian   +2 more
doaj   +1 more source

Creative Economy-Feasible Option for România [PDF]

open access: yes
The paper’s objective is the scientific foundation of the necessity to implement the topic of creative economy in Romania. The term of creative economy is widely used in the context of the knowledge-based society.
Maria-Liana LACATUS   +2 more
core  

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