Results 231 to 240 of about 2,965,464 (283)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Neural dynamics during the generation and evaluation of creative and non-creative ideas. [PDF]

Commun Biol
Kenett YN, Chrysikou EG, Bassett DS, Thompson-Schill SL.   +3 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Creativity and transition to bipolar disorder: a prospective analysis from the early-bipolife study. [PDF]

Int J Bipolar Disord
Michaelis E, Bauer M, Bechdolf A, Bermpohl F, Berndt C, Bröckel-Bundt KL, Burkhardt E, Correll CU, Dannlowski U, Falkenberg I, Fallgatter AJ, Fusar-Poli P, Hadji S, Jansen A, Juckel G, Kircher T, Kittel-Schneider S, Krüger-Özgürdal S, Lambert M, Leopold K, Maicher B, Matura S, Mennigen E, Mikolas P, Reif A, Ritter P, Sauer C, Stamm T, Martini J, Pfennig A.   +29 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Methodologies of Care: A Multimodal, Participatory Research Approach with Vulnerable Families Among South African Communities. [PDF]

Methods Protoc
Reid J, Johannes C, Wareley S, Ngadhi C, Nginase A, Demetriou K, Roman NV.   +6 more
europepmc   +1 more source

Integrating Creative Approaches to Dementia Care Into Nursing Programmes: Findings From an International Qualitative Study. [PDF]

Scand J Caring Sci
Tommasini C, Mantzoukas S, Buitenkamp C, van der Vaart N, Zampira I, Laiou E, Paschou A, Lazarou E, Makri M, Kuvajainen M, Liljeström V, de Haan N, van Ooijen M, Tsolaki M, Chiappinotto S, Palese A, Cadorin L.   +16 more
europepmc   +1 more source

Enhancing innovation in medical students through imaginative driven models. [PDF]

Sci Rep
Lufeng L, Das G, Gopang AA, Khuhro AS, Memon S.   +4 more
europepmc   +1 more source

The effect of negative feedback hierarchy on creativity: the mediating role of positive affect and strategy modification. [PDF]

BMC Psychol
Liu M, Zhao J, Pang W.
europepmc   +1 more source