Results 61 to 70 of about 73,896 (248)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

RUSSIA AND CHINA: THE MAIN AREAS OF DEVIANCE AT THE BEGINNING OF THE XXI CENTURY

open access: yesВестник университета, 2019
The article analyses the main forms of deviance in modern Russia and in modern China. Found that media of deviant behavior, both in Russia and in China, are recruited from all segments of society.
S. Yanli, M. Romanenko
doaj  

New Flexible Regression Models Generated by Gamma Random Variables with Censored Data [PDF]

open access: yes, 2016
We propose and study a new log-gamma Weibull regression model. We obtain explicit expressions for the raw and incomplete moments, quantile and generating functions and mean deviations of the log-gamma Weibull distribution.
Cordeiro, Gauss M.   +3 more
core   +1 more source

Analysis of mortality in a pooled cohort of Canadian and German uranium processing workers with no mining experience. [PDF]

open access: yes, 2017
PurposeLong-term health risks of occupational exposures to uranium processing were examined to better understand potential differences with uranium underground miners and nuclear reactor workers.MethodsA cohort study of mortality of workers from Port ...
Fenske, Nora   +5 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

RUSSIA AND CHINA: THE MAIN AREAS OF DEVIANCE AT THE BEGINNING OF THE XXI CENTURY

open access: yesВестник университета, 2017
The article analyses the main forms of deviance in modern Russia and in modern China. Found that media of deviant behavior, both in Russia and in China, are recruited from all segments of society.
S. Yanli, M. Romanenko
doaj  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Constructive Deviance, Destructive Deviance and Personality: How do they interrelate? [PDF]

open access: yes
In recent years deviant behavior in organizations has drawn increasing attention. However, surprisingly little research has focused on constructive rather than destructive deviance.
Aharon Tziner, Moran Bodankin
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

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