Results 31 to 40 of about 338 (165)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Characterization of the five-tier model of creative mathematical thinking in primary school learners

open access: yesAlifmatika
Creative mathematical thinking skills among elementary students remain relatively low, largely due to predominantly procedural instruction, highlighting the need to examine the characteristics of their innovative thinking stages in solving data ...
Ervita Tri Susilowati   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Entre diabolisation, séduction et légitimation. Le kitsch ou l’imitation comme « mal esthétique » ?

open access: yesCahiers d’Études Germaniques, 2017
On the basis of Clement Greenberg’s distinction between the avant-garde as “imitating the act of imitation” and kitsch as “imitating the effect of imitation” in order to provoke the pleasure of the senses, we will show that kitsch induces a “culinary ...
Florence BANCAUD
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Notes sur la part d’imitation dans l’innovation en architecture

open access: yesLes Cahiers de la Recherche Architecturale, Urbaine et Paysagère, 2018
Does an architect become innovative when they exhibit esthetically creative work, when they use new materials or when they engage unusual methods ?
Rémi Laporte
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

The Alphabet of Architecture. Originality and Literacy in the Theory of Profiles

open access: yesRA. Revista de Arquitectura, 2022
In 1691 Augustin-Charles D’Aviler published his Cours d’architecture qui comprend les ordres de Vignole. Ostensibly one of the many extended editions of Vignola’s Regola delli cinque ordini d’architettura (1562) that would appear over the course of the ...
Maarten Delbeke
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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