Results 31 to 40 of about 4,077 (254)
Entre diabolisation, séduction et légitimation. Le kitsch ou l’imitation comme « mal esthétique » ?
On the basis of Clement Greenberg’s distinction between the avant-garde as “imitating the act of imitation” and kitsch as “imitating the effect of imitation” in order to provoke the pleasure of the senses, we will show that kitsch induces a “culinary ...
Florence BANCAUD
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Notes sur la part d’imitation dans l’innovation en architecture
Does an architect become innovative when they exhibit esthetically creative work, when they use new materials or when they engage unusual methods ?
Rémi Laporte
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How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Imitation as Factor of Developing Higher Abilities in Children: Resource Approach
The phenomenon of “imitation” in children is analyzed. The possibility of the use of imitation for development of higher abilities (mostly creative) in children is studied.
G V Ozhiganova
doaj
The Alphabet of Architecture. Originality and Literacy in the Theory of Profiles
In 1691 Augustin-Charles D’Aviler published his Cours d’architecture qui comprend les ordres de Vignole. Ostensibly one of the many extended editions of Vignola’s Regola delli cinque ordini d’architettura (1562) that would appear over the course of the ...
Maarten Delbeke
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This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

