Results 61 to 70 of about 172,089 (291)
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Exploring children's development of ideas in music and dance [PDF]
, 2007 Eisner maintains that the Arts education community needs ‘empirically grounded examples of artistic thinking related to the nature of the tasks students engage in, the material with which they work, the context’s norms and the cues the teacher provides ...
Fraser, Deborah +2 more
core +1 more source
Simpler for evolution: Secondary representation in apes, children, and ancestors [PDF]
, 1998 Great apes show behavioural evidence for secondary representation similar to that of children of about two years of age. However, there is no convincing evidence for metarepresentation in apes.
Suddendorf, Thomas
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Entrepreneurships within Small and Medium Enterprises: A study of Entrepreneurs' Motivation in Nepal and India [PDF]
Journal of Interdisciplinary SciencesEntrepreneurship is an old concept, even existing during the barter system. Entrepreneurship development was a concern of becoming resourceful. Entrepreneurship exists in various organizations, not alone from management.
Mani Man Singh Rajbhandari
doaj
Communicative Aspect of Educational Process as a Category of Non-Classical Paradigm of Creativity
Образование и наука, 2015 The article considers the urgent problems of modern education related to creative consciousness development and acceptable imitation proportion. The author refers to the communication theory to show the interrelation between creativity and communicative ...
A. A. Kartashova
doaj +1 more source
"IMMORTALITY OF MY SOUL...": THE GENESIS OF PUSHKIN'S POEM EXEGI MONUMENTUM (I HAVE ERECTED A MONUMENT TO MYSELF) [PDF]
Проблемы исторической поэтики, 2013 Pushkin's overcoming of death is represented by two aspects of his work: stoical Christian acceptance of death and identification of immortality of a soul with creative heritage.
Lyudmila Vasilyevna Stebeneva
doaj +1 more source
How Creative Should Creators be to Optimize the Evolution of Ideas? A Computer Model [PDF]
, 2009 There are both benefits and drawbacks to creativity. In a social group it is not necessary for all members to be creative to benefit from creativity; some merely imitate or enjoy the fruits of others' creative efforts. What proportion should be creative?
Gabora, Dr. Liane, Leijnen, Stefan
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source