Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Literature Review of the Definition, Size and Turnover of the Creative Industries and Micro-Businesses in Scotland: Preliminary Research [PDF]
, 2013 This research seeks to review, evaluate and clarify the findings of five recent reports in relation to the discussion paper Creative Industries in Scotland.
Sorensen, Inge
core
Efficiency Measurement and Heterogeneity Analysis of Chinese Cultural and Creative Industries: Based on Three-Stage Data Envelopment Analysis Modified by Stochastic Frontier Analysis. [PDF]
Front Psychol, 2021 Li M, Sun H, Agyeman FO, Su J, Hu W.
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Creative economy employment in the EU and the UK: a comparative analysis [PDF]
, 2015 Analysts and policymakers have long complained of the dearth of internationally comparable statistics on the creative industries because it has made it impossible to benchmark the performance of different countries.
Nathan, M. +2 more
core
Thermoplastic polyurethane flexible capacitive proximity sensor reinforced by CNTs for applications in the creative industries. [PDF]
Sci Rep, 2021 Moheimani R +4 more
europepmc +1 more source
, 2012 O artigo traça um painel das discussões sobre indústrias criativas, trazendo as diversas visões e definições sobre o tema, suas relações com outras áreas do conhecimento e da economia, discorrendo ainda sobre seus aspectos econômicos e apresentando um panorama das políticas públicas para o setor.
openaire +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Creative industries and global education [PDF]
, 2016 The creative industries are the fastest-growing area of the United Kingdom economy and a catalyst for global development. This paper explores how one UK university connects cultures of creative education across national boundaries, ensuring our students ...
Slade, C
core