Results 41 to 50 of about 2,059,009 (310)

The Role of Local and Regional Factors in the Development of Creative Clusters

Studia i Materiały, 2017
Creative industries tend to concentrate around large and medium cities forming creative local production systems. The article will present literature review focused on the role of creative cities in such aspects as: knowledge centers, entrepreneurship ...
Anna Szopa
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

A Behavioral Approach Design for Supporting Sitting Facilities at The Lounge Area Of Minangkabau International Airport (BIM)

Mudra: Jurnal Seni Budaya
Minangkabau International Airport (BIM) located in West Sumatera is used as the main air transportation mode to travel outside the province. When waiting for flights, passengers will be in the airport lounge.
Faiz Alghifary, Imtihan Hanom
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

“Communal News Work” as Sustainable Business Model: Recent Print-Centric News Start-Ups in Regional Queensland

Media and Communication
The Covid-19 emergency in Australia precipitated the closure of dozens of print newspapers across Australia but, conversely, the heightened state of anxiety of the early Covid-19 period amplified the need for local information and communality.
Harry Dugmore, Renee Barnes, Peter English, Elizabeth J. Stephens, Rosanna Natoli   +4 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Generative AI in Higher Education: A Structured Integrative Literature Review of Student–Staff Partnership, Responsible Use, and Inclusive Learning

Information
Generative artificial intelligence (GenAI) is reshaping higher education, yet its educational value, governance, inclusion and responsible implementation remain contested.
Antesar Shabut, Vishvapriya Sangvikar, Xin Lu, Adekemi Yewande Karimu, Chisom Nwoko   +4 more
doaj   +1 more source

Artificial intelligence in project management: A bibliometric analysis [PDF]

Problems and Perspectives in Management
This study explores the integration of artificial intelligence (AI) into project management through a bibliometric analysis of scholarly publications and patents from 2001 to 2024.
Nurkhat Ibadildin, Zhaxat Kenzhin, Gaukhar Yeshenkulova, Rymkul Ismailova, Assel Nurguzhina, Samalgul Nassanbekova, Aiman Kadyrova   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source