Results 41 to 50 of about 19,667 (261)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

A Behavioral Approach Design for Supporting Sitting Facilities at The Lounge Area Of Minangkabau International Airport (BIM)

open access: yesMudra: Jurnal Seni Budaya
Minangkabau International Airport (BIM) located in West Sumatera is used as the main air transportation mode to travel outside the province. When waiting for flights, passengers will be in the airport lounge.
Faiz Alghifary, Imtihan Hanom
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

“Communal News Work” as Sustainable Business Model: Recent Print-Centric News Start-Ups in Regional Queensland

open access: yesMedia and Communication
The Covid-19 emergency in Australia precipitated the closure of dozens of print newspapers across Australia but, conversely, the heightened state of anxiety of the early Covid-19 period amplified the need for local information and communality.
Harry Dugmore   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Urban Connective Action: The Case of Events Hosted in Public Space

open access: yesUrban Planning, 2020
In the past decade, significant transformations have influenced the governance of urban public spaces. There has also been a growth in new public spheres associated with digital media networks, informing and influencing the production and regulation of ...
David McGillivray   +2 more
doaj   +1 more source

Adapting, surviving, discovering: Creative practitioners in the COVID-19 crisis

open access: yesJournal of Creativity, 2022
This study investigates how the COVID-19 pandemic affected the work and creative practice of individuals who identify as artists, producers or makers.
Valeria Duarte, David Gauntlett
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Artificial intelligence in project management: A bibliometric analysis [PDF]

open access: yesProblems and Perspectives in Management
This study explores the integration of artificial intelligence (AI) into project management through a bibliometric analysis of scholarly publications and patents from 2001 to 2024.
Nurkhat Ibadildin   +6 more
doaj   +1 more source

Culturally conditioned visual communication in creative expression

open access: yesCreativity Studies, 2020
The human body and its consciousness interacts with a number of external and internal factors, including, among others, the surrounding environment, experienced emotions, those things seen, things that are possessed and touched, and affection that is ...
Ilona Valantinaitė   +2 more
doaj   +1 more source

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