Results 131 to 140 of about 3,602,415 (283)
Creative processes in visual arts in education: a conceptual framework
Creativity StudiesThe diversity and uniqueness of individuals and the multifaceted nature of creativity necessitate new models in various domains. This study reviewed previous studies and models of the creative process and presented a combined model (Swanzy-Impraim ...
Enock Swanzy-Impraim
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Back to Life: Leadership from a Process Perspective [PDF]
, 2010 Process thinking has given us signals regarding how to make critical judgements about, or else how to grasp actively and immanently, an organisational world on the move.
Wood, M.
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Relacionando o planejamento de produto ao processo criativo: uma proposta
Revista Produção Online, 2003 This work presents some considerations about creativity in like manner than establishing connections between creative process stages and industrial product planning.
Cesar Antônio Mantovani +1 more
doaj
Critique [of Chicano Ethnicity and Aging by Marvin A. Lewis] [PDF]
, 1985 Lewis\u27s article presents a creative and exciting approach for understanding the importance elderly people have not only in the family but in the community as well. He blends literary personification, cultural integration, and social science strategies
Hiura, Barbara L.
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Pushing the boundaries: a study of higher education students’ responses to a creative, art-based learning experience. [PDF]
, 2014 This article examines students’ responses to an open-ended, art-based task which involved the documentation of the creative process and culminated in the production of individual art pieces.
Watson, Janice
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source