Results 131 to 140 of about 3,621,799 (301)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Creative processes in visual arts in education: a conceptual framework
Creativity StudiesThe diversity and uniqueness of individuals and the multifaceted nature of creativity necessitate new models in various domains. This study reviewed previous studies and models of the creative process and presented a combined model (Swanzy-Impraim ...
Enock Swanzy-Impraim
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Back to Life: Leadership from a Process Perspective [PDF]
, 2010 Process thinking has given us signals regarding how to make critical judgements about, or else how to grasp actively and immanently, an organisational world on the move.
Wood, M.
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Relacionando o planejamento de produto ao processo criativo: uma proposta
Revista Produção Online, 2003 This work presents some considerations about creativity in like manner than establishing connections between creative process stages and industrial product planning.
Cesar Antônio Mantovani +1 more
doaj
Creativity and positive emotions in studying: Novel possibilities for improving students’ learning [PDF]
, 2014 Research on students’ learning identified that positive affect is a strong predictor of better academic performance even when statistically controlling for effects of prior academic performance and approaches to learning (e.g., Rogaten, Moneta & Spada ...
Moneta, Giovanni B, Rogaten, Jekaterina
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Creative Process Beyond the Studio [PDF]
, 2012 Creative Process Beyond the Studio In “Creativity: Flow and the Psychology of Discovery and Invention,” psychologist Mihaly Csikszentmihalyi offers the idea that “…creativity does not happen inside people’s heads, but in the interaction between a person ...
Aubert, Danielle +4 more
core +1 more source