Results 171 to 180 of about 155,339 (259)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Exploring the impact of AI tools on filmmakers' creative satisfaction: the mediating role of creative efficiency and autonomy. [PDF]

Front Psychol
Jiang W, Zheng J.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The way we do things matters: the deep integration of lived experience in the a/part of the crowd project to respond to loneliness in young adults. [PDF]

Res Involv Engagem
Peart C, Lewis M, Bibb J, Read G, Tesfu K, Rathore K, Tan LX, Wong T, Turner A, Andalib F, Ziero G, Rule J, Cao L, Merritt L, Rezaie N, Shelton T, Kaylor-Hughes C, Coe A, Orcher Muruwori/Gumbaynggirr P, Palmer VJ.   +19 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Integrating Creative and Community Health Services into Clinical Workstreams: A Qualitative Case Study from Gloucestershire Integrated Care Board

Hearst J, Chatterjee HJ, Penn F, Gorf H.
europepmc   +1 more source

Neuroscience-Informed Creative Group Therapy for Processing Trauma and Developing Resilience During Wartime. [PDF]

J Pers Med
Vaisvaser S, Shalem-Zafari Y, Ram-Vlasov N, Shamri-Zeevi L.   +3 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Dance/movement therapy in psychotic disorders and eating disorders: a systematic review. [PDF]

Front Psychiatry
Monaco F, Vignapiano A, Landi S, Panarello E, Malvone R, Pullano I, Fiore G, Iazzolino AM, Steardo L, Sosto G, Corrivetti G.   +10 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source