Results 171 to 180 of about 1,391,241 (279)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Differentiated Hypermedia E-Module for Social Studies (EduHYPE-IPS): Enhancing Creative Thinking Skills of Elementary School Students. [PDF]

F1000Res
Haryanti YD, Sumantri MS, Mahpudin M, Sapriya S, Atmaja HT, Dewi SM, Santika O, Nurhadiansyah L, Putri MT.   +8 more
europepmc   +1 more source

Free Your Mind: Creative Thinking Contributes to Overcoming Conflict-Related Biases. [PDF]

Brain Sci, 2022
Fahoum N, Pick H, Ivancovsky T, Shamay-Tsoory S.   +3 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Enhanced creative thinking performance: the role of alpha frequency transcranial alternating current stimulation in the parieto-occipital region. [PDF]

BMC Psychol
Zhou R, Wang J, Man X, Huang X, Zhan A, Liu C, Yang J.   +6 more
europepmc   +1 more source

The default network is causally linked to creative thinking. [PDF]

Mol Psychiatry, 2022
Shofty B, Gonen T, Bergmann E, Mayseless N, Korn A, Shamay-Tsoory S, Grossman R, Jalon I, Kahn I, Ram Z.   +9 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Exploring creative thinking skills in PISA: an ecological perspective on high-performing countries. [PDF]

Front Psychol
Gelmez Burakgazi S, Reiss MJ.
europepmc   +1 more source

What do educators need to know about the Torrance Tests of Creative Thinking: A comprehensive review. [PDF]

Front Psychol, 2022
Alabbasi AMA, Paek SH, Kim D, Cramond B.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source