Results 71 to 80 of about 707,370 (302)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
The challenges of revenue generation in state universities: The case of Zimbabwe
Cogent Social Sciences, 2020 The study examined the challenges on revenue generation among state universities in Zimbabwe. The situation at state universities is unbearable because of rising inflation, worsening economic and political challenges facing Zimbabwe for close to three ...
Andrias Chinyoka, Emmanuel Mutambara
doaj +1 more source
The internationalisation of emerging market higher education providers: exploring transnational provision [PDF]
, 2015 The delivery of transnational higher education by emerging market providers is a relatively new phenomenon -- While much has been written about mainly British, U.S.
Rusell, Eliza
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Training Competences in Industrial Risk Prevention with Lego® Serious Play®: A Case Study [PDF]
, 2019 This paper proposes the use of the Lego® Serious Play® (LSP) methodology as a facilitating tool for the introduction of competences for Industrial Risk Prevention by engineering students from the industrial branch (electrical, electronic, mechanical and ...
Aguayo-González, Francisco +5 more
core
The travelling sonnet: The key role of technology in an inter-university cultural heritage project [PDF]
, 2015 Students on the undergraduate degree in Primary Education in Spain took part in this inter-university experience within the subject of Didactics of Musical Expression.
arriaga, cristina +4 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Discover EducationThe rapid digital turn tested universities' resilience like never before. New modes of survival and creative actions were required to cope with the COVID-19 crisis and the extreme upheaval of established ways of teaching.
Melissa Laufer +3 more
doaj +1 more source