Results 151 to 160 of about 197,143 (309)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Creative Writing Methods for Collective and Regenerative Thinking [PDF]

open access: yes
This article asks how creative practice researchers — ordinarily working in disparate fields — might find common ground to speak across disciplines in addressing important issues and shared problems.
Mazzarella, Francesco
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Characterization of the Stages of Creative Writing With Mobile EEG Using Generalized Partial Directed Coherence. [PDF]

open access: yesFront Hum Neurosci, 2020
Cruz-Garza JG   +4 more
europepmc   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Creative writing as a tool in rehabilitation and educational work

open access: yes, 2015
Keynote talk to Creative Writing Pedagogy and Well-Being conference Jyväskylä, 22.10 ...
Sučylaitė, Jūratė
core  

The Undergraduate Creative Writing Workshop [PDF]

open access: yes, 2009
More and more institutions are offering undergraduate Creative Writing Programmes. Many of these offer the workshop as part of that programme. The undergraduatecreative writing workshop differs from the postgraduate one and is also different from ...
James, G
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Exo-autoethnography : writing and research on transgenerational transmission of trauma

open access: yes, 2016
Since the late 1970s, autoethnographic research and writing has demonstrated that non-fiction creative writing practice can utilise this alternate-ethnographic method as part of its research and narrative, producing rigorous creative work which is ...
Denejkina, Anna (R19494)
core  

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