Results 171 to 180 of about 2,449,132 (295)

Characterizing Features of Creative Writing in Older Adults. [PDF]

J Gerontol B Psychol Sci Soc Sci
Orwig W, Schacter DL.
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Creative writing in medical ethics: reflections on reflective practice. [PDF]

Br J Gen Pract
Roberts W.
europepmc   +1 more source

Creative writing under the ERA writing under duress, but relatively happy /

, 2012
The Excellence in Research for Australia (ERA) research evaluation process includes creative work, including creative writing. This article discusses the effect that writing under the ERA is having on academics in creative writing, including probing the ...
Donna Brien (9783098), Brien, Donna Lee., Krauth, Nigel., N Krauth (9868901)   +3 more
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

New Chaotic Reality: Creative Writing Workshops for Long COVID Patients. [PDF]

J Med Humanit
Garland E.
europepmc   +1 more source

Proxy Users Enable Older People Creative Writing on the Web. [PDF]

Front Sociol, 2019
Toczyski P, Kowalski J, Biele C.
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Participation in a Physician Creative Writing Community: 15-Year Program Survey Outcomes at an Academic Medical Center. [PDF]

J Gen Intern Med
Pien J, Ali TK, Schlozman S, Jamal A, Bucknor MD, Srinivasan M.   +5 more
europepmc   +1 more source

Use of Creative Writing to Develop a Semantic Differential Tool for Assessing Soundscapes. [PDF]

Front Psychol, 2018
Welch D, Shepherd D, Dirks K, Tan MY, Coad G.   +4 more
europepmc   +1 more source