Results 131 to 140 of about 200,908 (303)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
<b>External Organisations</b><br/>University of Florida; University of Michigan<b>Associated Persons</b><br/>Ricky Hu (Creator); Armin Patrick Scheben (Creator); Brent Verpaalen (Creator)Richard G.J.
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
ASKAP/WALLABY Early Science Project AS035 - HI Spectral Cube of the NGC 7232 Galaxy Group
<b>Associated Persons</b><br/>Jing Wang (Creator)Baerbel Koribalski (Creator); Dane Kleiner (Creator); Juan Madrid Gamboa (Creator); Paolo Serra (Creator); Li Shao (Creator); Matthew Whiting (Creator); James R.
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
<b>Associated Persons</b><br/>Roberto Forero (Creator); Peter Carl Sprivulis (Creator)Wing Nicola Man (Creator); Mohammed Mohsin (Creator); Sam Toloo (Creator); Gerard Fitzgerald (Creator); Sally Mccarthy (Creator); Ken Hillman (Creator)
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Oriki Eledumare (Praise of the Creator) by Mayowa Adeyemo
Performance: Mayowa Adeyemo +2348039220116 Videography: Aaron Carter-Ényì Translation: Mayowa Adeyemo Captioning: Aaron Carter-Ényì Interviewer: David Aina Description: Aaron Carter-Ényì In this video, Mayowa Adeyemo praises Eledumare (Yoruba for Creator)
core
ASKAP Data Products for Project AS102 (ASKAP Pilot Survey for WALLABY): catalogues
<b>External Organisations</b><br/>Commonwealth Scientific & Industrial Research Organisation; Swinburne University of Technology; National Institute for Astrophysics; CSIRO - Space and Astronomy; Royal Military College of Canada<b>
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