Results 161 to 170 of about 87,086 (298)

Sleeve gastrectomy improves cognition by enhancing central ERK/CREB/BDNF pathway through increased GIP secretion. [PDF]

iScience
Wei Z, Yang J, Qiao Y, Wang S, Cai Y, Gao L.   +5 more
europepmc   +1 more source

Could Incretin‐Based Weight Loss Unmask a Modifiable Nociplastic Pain Phenotype? A Rheumatological Reading of SURMOUNT‐5

Diabetes, Obesity and Metabolism, EarlyView.
Jacopo Ciaffi, Roberto Caporali, Francesco Ursini   +2 more
wiley   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Neuroinflammation promotes the development of pharmacoresistant epilepsy by triggering the MSK1/CREB signaling pathway. [PDF]

Sci Rep
Shi D, Niu Z, Li L, Wang L, Ren S, Li J, Wu G.   +6 more
europepmc   +1 more source

The role of CREB and the cAMP/PKA/CREB signaling pathway in sleep and memory

, 2002
Studies have demonstrated that mice with low levels of the CREB protein (CREB αΔ mice) on a mixed genetic background have impaired hip pocampus-dependent memory. One question is whether impairments of memory seen in CREB αΔ mice are due to the effects of
Graves, Laurel Ann
core  

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

<i>Erratum</i> to: "Multilevel defects in the hematopoietic niche in essential thrombocythemia". [PDF]

Haematologica
Sun T, Ju M, Dai X, Dong H, Gu W, Gao Y, Fu R, Liu X, Huang Y, Liu W, Ch Y, Wang W, Li H, Zhou Y, Shi L, Yang R, Zhang L.   +16 more
europepmc   +1 more source

Maximal exercise at high altitude does not exacerbate inflammation in the human brain

The Journal of Physiology, EarlyView.
Abstract figure legend This study investigated arterial–internal jugular venous (IJV) exchange of cytokines in response to low‐intensity and maximal cycling exercise at sea level and following 6–8 days at 3800 m a.s.l. There was a shift towards net release of interleukin‐6 (IL‐6), interleukin‐8 (IL‐8), monocyte chemoattractant protein‐1 (MCP‐1) and ...
Hannah G. Caldwell, Travis D. Gibbons, Connor A. Howe, Jack S. Talbot, Elliott J. Jenkins, L. Madden Brewster, Justin A. Monteleone, Jay M. J. R. Carr, Andrew R. Steele, Michael Stembridge, David B. MacLeod, Philip N. Ainslie   +11 more
wiley   +1 more source

Cordycepin alleviates nicotine withdrawal-induced anxiety <i>via</i> AMPK/CREB/BDNF pathway activation in the hippocampus of male mice. [PDF]

Drug Alcohol Depend Rep
Wang T, Tian S, He M, Tang S, Ji X, Deng Q, Zhang W, Jin G, Mao J, Zhang H.   +9 more
europepmc   +1 more source

Stac2 genetic deletion alters mouse chromaffin cells’ CaV channel composition, increases membrane excitability and reduces vesicle exocytosis

The Journal of Physiology, EarlyView.
Abstract figure legend Stac2 adaptor protein is expressed in neurons and endocrine cells. Using a global Stac2 knockout mouse model here we investigated the role of endogenous Stac2 in adrenal gland mouse chromaffin cell (MCC) excitability and catecholamine vesicle exocytosis.
Stefanie M. Geisler, Noelia Jacobo‐Piqueras, Tamara Theiner, Ryoichi S. Taguchi, Laura E. Häfele, Marta Campiglio, Petronel Tuluc   +6 more
wiley   +1 more source