Mesenchymal stromal cells modulate survival and regeneration of human hematopoietic stem cells via PGE2/cAMP signaling. [PDF]
Muddineni SSNA +15 more
europepmc +1 more source
Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen +14 more
wiley +1 more source
KLF7 induced ADRB3-dependent IL-6 production in brown adipocytes during stress. [PDF]
Liang M +15 more
europepmc +1 more source
GLP‐1 agonists and the gut microbiome: A bidirectional relationship
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath +2 more
wiley +1 more source
TAAR1-mediated pathways regulating nigrostriatal function and the discovery and pharmacological characterization of a novel TAAR1 agonist, Selutaront. [PDF]
Zhang J +8 more
europepmc +1 more source
Calcineurin controls the expression of numerous genes in cerebellar granule cells [PDF]
Ashby, Dominique S +4 more
core +1 more source
Distinct music frequencies used are as follows: – 528 Hz → BDNF & CREB (learning, memory, and neuroplasticity). – 432 Hz → GRP78 (cellular stress response marker). – Stroop Test → No immediate cognitive difference. Note that a frequency of 528 Hz showed a pattern compatible with enhanced neurotrophic signaling, while a frequency of 432 Hz was linked to
Ümmü Gülşen Bozok +3 more
wiley +1 more source
ELK1 suppressed the progression of vascular dementia via modulating mTOR/CREB/YAP/TFEB signaling induced ferroptosis in hippocampal cells. [PDF]
Xu J +11 more
europepmc +1 more source
Oncogenic driver and therapeutic target: Prolactin signalling axis in retroperitoneal sarcoma
Retroperitoneal sarcoma cells can secrete prolactin into the bloodstream, inducing hyperprolactinaemia, which subsequently triggers metabolic reprogramming, such as glucose metabolism. SOX4 can function as a transcription factor that facilitates PRL transcription.
Fu'an Xie +21 more
wiley +1 more source
PRKACB Attenuates Chondrocyte Loss and Inflammation in Osteoarthritis. [PDF]
Xiao W, Liu Z, Zhang Q.
europepmc +1 more source

