The intravenous and oral pharmacokinetics of lotilaner in dogs [PDF]
Background Lotilaner is a new oral ectoparasiticide from the isoxazoline class developed for the treatment of flea and tick infestations in dogs. It is formulated as pure S-enantiomer in flavoured chewable tablets (Credelio™).
Céline E. Toutain +2 more
doaj +3 more sources
A randomised, blinded, controlled field study to assess the efficacy and safety of lotilaner tablets (Credelio™) in controlling fleas in client-owned dogs in European countries [PDF]
Background Lotilaner is a novel isoxazoline developed for oral administration to dogs. In laboratory studies, lotilaner was shown to be safe and to produce a rapid flea and tick knockdown, with a sustained speed of kill for at least a month post ...
Daniela Cavalleri +4 more
doaj +3 more sources
Efficacy of lotilaner (Credelio™) against the adult cat flea, Ctenocephalides felis and flea eggs following oral administration to dogs [PDF]
Background A blinded, randomized, negative controlled laboratory study was conducted to evaluate the efficacy of lotilaner (CredelioTM, Elanco) when administered orally to dogs, against experimentally induced adult flea infestations and flea egg ...
Lisa Young +3 more
doaj +2 more sources
Efficacy of Credelio Quattro™ (lotilaner, moxidectin, pyrantel, praziquantel) and Credelio™ (lotilaner) against longhorned tick, Haemaphysalis longicornis,-induced infestations on dogs [PDF]
Background Haemaphysalis longicornis, the longhorned tick, is an invasive tick species that has been identified in increasing numbers and regions across the USA.
Scott Wiseman +5 more
doaj +2 more sources
Efficacy of Credelio Quattro™ (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets) and Credelio™ (lotilaner) chewable tablets in the prevention of Borrelia burgdorferi transmission from infected Ixodes scapularis in dogs [PDF]
Background Borrelia burgdorferi, the causative agent of Lyme disease, is a zoonotic vector-borne pathogen transmitted by various Ixodes tick species. Lyme disease, while commonly asymptomatic, can induce fever and intermittent lameness in dogs.
William Anderson +5 more
doaj +2 more sources
Laboratory evaluation of the efficacy of lotilaner (Credelio™) against Amblyomma cajennense (sensu lato) infestations of dogs [PDF]
Background The ixodid tick Amblyomma cajennense (sensu lato) complex, widespread throughout South and Central America, is also present in Mexico, Texas and Florida.
Pedro Veloso Facury Lasmar +7 more
doaj +2 more sources
Field efficacy and safety evaluation of a novel chewable tablet (Credelio Quattro™) containing lotilaner, moxidectin, praziquantel, and pyrantel against gastrointestinal nematode infections in dogs in the USA [PDF]
Background Gastrointestinal nematodes such as hookworms (Ancylostoma caninum) and roundworms (Toxocara canis) commonly infect dogs and are zoonotic parasites capable of producing clinical disease in humans.
Samuel Charles +4 more
doaj +2 more sources
Efficacy of lotilaner against myiasis caused by Cochliomyia hominivorax (Diptera: Calliphoridae) in naturally infested dogs [PDF]
Background The New World screwworm fly, Cochliomyia hominivorax, is widely distributed across South America. This parasitic insect is a significant cause of primary myiasis in animals, including dogs.
Tássia Lopes do Vale +9 more
doaj +2 more sources
A randomized, controlled field study to assess the efficacy and safety of lotilaner (Credelio™) in controlling fleas in client-owned cats in Europe [PDF]
Background Lotilaner is a new isoxazoline developed as an oral ectoparasiticide for cats and dogs. Its safety, rapid killing onset of action and sustained speed of fleas and ticks kill for a minimum of one month after administration, were demonstrated in
Daniela Cavalleri +3 more
doaj +2 more sources
Long-term safety of Credelio Quattro™ (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets), a novel orally administered combination endectocide for dogs [PDF]
Background The combination of lotilaner, moxidectin, praziquantel, and pyrantel pamoate (Credelio Quattro) is a novel systemic endectocide that provides month-long effectiveness in dogs after a single oral treatment.
Kari L. Riggs +2 more
doaj +2 more sources

