Lotilaner ophthalmic solution 0.25% in the treatment of blepharitis: A case report [PDF]
Demodex blepharitis is a chronic inflammatory ocular condition caused by Demodex mite infestation of the eyelid that can negatively impact quality of life.
Paul Karpecki +14 more
doaj +5 more sources
Oral Lotilaner in 21 Cats With Naturally Acquired Harvest Mite Infestation. [PDF]
Case series summary This case series describes 21 client-owned cats with naturally acquired harvest mite infestation treated with a single oral dose of lotilaner.
Elisa Maina, Carlotta Filippini
exaly +4 more sources
Safety and Efficacy of Lotilaner Ophthalmic Solution (0.25%) in Treating Demodex Blepharitis: Pooled Analysis of Two Pivotal Trials [PDF]
Introduction Lotilaner ophthalmic solution (0.25%) is the first United States Food and Drug Administration (US FDA)-approved drug for treating Demodex blepharitis.
Gregg J Berdy, Cecelia Koetting
exaly +4 more sources
Impact of Lotilaner Ophthalmic Solution 0.25% on Disease Severity in Patients With Demodex Blepharitis and Meibomian Gland Disease [PDF]
PurposeTo evaluate the impact of lotilaner ophthalmic solution, 0.25%, compared to vehicle, on disease severity in patients with Demodex blepharitis and meibomian gland disease.MethodsThis post-hoc analysis pooled data from two prospective, randomized ...
Elizabeth Yeu, Bridgitte Shen Lee
exaly +4 more sources
Efficacy of lotilaner (Credelio™ chewable tablets) for preventing Babesia canis transmission to dogs by infected Dermacentor reticulatus ticks [PDF]
Background Canine babesiosis is a clinically significant tick-borne disease, caused by different Babesia species. Babesia canis, one of the most important and widespread species in Europe, is transmitted by Dermacentor reticulatus ticks and can cause ...
Katrin Deuster +7 more
doaj +3 more sources
Effectiveness of lotilaner on furuncular myiasis in dogs naturally infested with Dermatobia hominis (Diptera: Cuterebridae) [PDF]
An evaluation was made of the larvicidal efficacy of lotilaner (Credeli®) in the treatment of dogs naturally infested with Dermatobia hominis larvae. A total of 12 dogs presenting at least three live D. hominis larvae were medicated.
Rafaella Tortoriello +4 more
doaj +4 more sources
Comparative speed of kill of induced Ixodes scapularis infestations following treatment of dogs with endectocides containing either sarolaner (Simparica Trio™), afoxolaner (NexGard® PLUS), or lotilaner (Credelio Quattro™) [PDF]
Background Ixodes scapularis is a consequential tick species in North America that can transmit multiple pathogens of canine and public health significance. Acaricidal speed is critical for reducing the risk of pathogen transmission.
Kathryn E. Reif +13 more
doaj +3 more sources
Systematic literature review and meta-analysis of lotilaner 0.25% and tea tree oil for Demodex blepharitis [PDF]
IntroductionDemodex blepharitis (DB) is a common, often underdiagnosed inflammatory eyelid disease caused by Demodex mite infestation. Currently, the only FDA-approved treatment for DB is lotilaner ophthalmic solution, 0.25%.
Ian Benjamin Gaddie +11 more
doaj +2 more sources
Comparative speed of kill provided by lotilaner (Credelio™), sarolaner (Simparica Trio™), and afoxolaner (NexGard™) to control Amblyomma americanum infestations on dogs [PDF]
Abstract Background Canine acaricides with rapid onset and sustained activity can reduce pathogen transmission risk and enhance pet owner experience.
Kathryn E. Reif +10 more
doaj +2 more sources
A novel method for the determination of isoxazoline derivatives in plasma by ultra-high performance liquid chromatography–tandem mass spectrometry: validation and applicability to screening tests [PDF]
Isoxazoline derivatives such as fluralaner, sarolaner, lotilaner, and afoxolaner are a new class of insecticide and acaricide compounds. These compounds are characterised by rapid action and high efficacy over a period of up to several weeks.
Markowska-Buńka Paulina +3 more
doaj +2 more sources

