Results 1 to 10 of about 297 (98)

Impact of lotilaner ophthalmic solution 0.25% on disease severity in patients with Demodex blepharitis and meibomian gland disease [PDF]

Frontiers in Medicine
PurposeTo evaluate the impact of lotilaner ophthalmic solution, 0.25%, compared to vehicle, on disease severity in patients with Demodex blepharitis and meibomian gland disease.MethodsThis post-hoc analysis pooled data from two prospective, randomized ...
Elizabeth Yeu, Eric Donnenfeld
exaly   +4 more sources

Safety and Efficacy of Lotilaner Ophthalmic Solution (0.25%) in Treating Demodex Blepharitis: Pooled Analysis of Two Pivotal Trials [PDF]

Ophthalmology and Therapy
Introduction Lotilaner ophthalmic solution (0.25%) is the first United States Food and Drug Administration (US FDA)-approved drug for treating Demodex blepharitis.
Elizabeth Yeu
exaly   +3 more sources

Comparative speed of kill of induced Ixodes scapularis infestations following treatment of dogs with endectocides containing either sarolaner (Simparica Trio™), afoxolaner (NexGard® PLUS), or lotilaner (Credelio Quattro™) [PDF]

Parasites & Vectors
Background Ixodes scapularis is a consequential tick species in North America that can transmit multiple pathogens of canine and public health significance. Acaricidal speed is critical for reducing the risk of pathogen transmission.
Kathryn E. Reif, Todd M. Kollasch, Casey L. Locklear, Matthew D. Eberts, Kayla N. Braswell, Anastasia M. W. Cooper, James W. Gillespie, Brian H. Herrin, Jonas P. McAbee, Carter M. Morgan, Anna Grace Morrow, Bailey J. Sperling, Daniel J. Sweeney, William G. Ryan   +13 more
doaj   +2 more sources

Lotilaner ophthalmic solution 0.25% in the treatment of blepharitis: A case report [PDF]

SAGE Open Medical Case Reports
Demodex blepharitis is a chronic inflammatory ocular condition caused by Demodex mite infestation of the eyelid that can negatively impact quality of life.
Paul Karpecki, Brandon Ayres, Eric Donnenfeld, Marjan Farid, Ian Benjamin Gaddie, Preeya K. Gupta, Cecelia Koetting, Richard Lindstrom, Selina McGee, Kelly K. Nichols, Laura M. Periman, Stephen Pflugfelder, Christopher Starr, Nandini Venkateswaran, Elizabeth Yeu   +14 more
doaj   +2 more sources

Pharmacokinetics of lotilaner following a single oral or intravenous administration in cats

Parasites and Vectors, 2018
Background CredelioTM (lotilaner) is an oral ectoparasiticide from the isoxazoline class developed for the treatment of flea and tick infestations in cats. It is formulated as a pure S-enantiomer in flavoured chewable tablets.
Celine Toutain, Wolfgang Seewald
exaly   +3 more sources

Efficacy of lotilaner (Credelio™ chewable tablets) for preventing Babesia canis transmission to dogs by infected Dermacentor reticulatus ticks [PDF]

Parasites & Vectors
Background Canine babesiosis is a clinically significant tick-borne disease, caused by different Babesia species. Babesia canis, one of the most important and widespread species in Europe, is transmitted by Dermacentor reticulatus ticks and can cause ...
Katrin Deuster, Laura A. Webb, Carin Rautenbach, William E. Anderson, Reinier Zwiegers, Friederike Krämer, Brad Hayes, Lisa Young   +7 more
doaj   +2 more sources

Effectiveness of lotilaner on furuncular myiasis in dogs naturally infested with Dermatobia hominis (Diptera: Cuterebridae) [PDF]

Revista Brasileira de Parasitologia Veterinária
An evaluation was made of the larvicidal efficacy of lotilaner (Credeli®) in the treatment of dogs naturally infested with Dermatobia hominis larvae. A total of 12 dogs presenting at least three live D. hominis larvae were medicated.
Rafaella Tortoriello, Luisa Xavier Christ, Victoria Caroline de Almeida Marques, Bruna Sampaio Martins, Julio Israel Fernandes   +4 more
doaj   +2 more sources

A novel method for the determination of isoxazoline derivatives in plasma by ultra-high performance liquid chromatography–tandem mass spectrometry: validation and applicability to screening tests [PDF]

Journal of Veterinary Research
Isoxazoline derivatives such as fluralaner, sarolaner, lotilaner, and afoxolaner are a new class of insecticide and acaricide compounds. These compounds are characterised by rapid action and high efficacy over a period of up to several weeks.
Markowska-Buńka Paulina, Jaroszewski Jerzy J., Rasiński Bartosz, Ziółkowski Hubert   +3 more
doaj   +2 more sources

Comparative speed of kill provided by lotilaner (Credelio™), sarolaner (Simparica Trio™), and afoxolaner (NexGard™) to control Amblyomma americanum infestations on dogs [PDF]

Parasites & Vectors
Abstract Background Canine acaricides with rapid onset and sustained activity can reduce pathogen transmission risk and enhance pet owner experience.
Kathryn E. Reif, Todd M. Kollasch, Jacqueline C. Neilson, Brian H. Herrin, William G. Ryan, Marjorie C. Bell, Mallory S. Beltz, Michael W. Dryden, Jeba R. J. Jesudoss Chelladurai, Kamilyah R. Miller, Cameron J. Sutherland   +10 more
doaj   +2 more sources

Oral lotilaner in 21 cats with naturally acquired harvest mite infestation [PDF]

Journal of Feline Medicine and Surgery
Case series summary This case series describes 21 client-owned cats with naturally acquired harvest mite infestation treated with a single oral dose of lotilaner.
Carlotta Filippini, Marion Etter, Elisa Maina   +2 more
doaj   +2 more sources