Results 41 to 50 of about 405 (122)

Efficacy of lotilaner (Credelio™) against experimentally induced infestations of the adult cat flea, Ctenocephalides felis, and flea eggs following oral administration to cats

Parasites & Vectors, 2021
Background Credelio™ (lotilaner; Elanco) is indicated for the treatment of flea and tick infestations on cats at a recommended lotilaner dose rate of 6–24 mg/kg.
Tandy Paarlberg, Daniela Karadzovska, Rainer Helbig   +2 more
doaj   +1 more source

Long-term safety of Credelio Quattro™ (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets), a novel orally administered combination endectocide for dogs [PDF]

Parasites and Vectors
Scott Wiseman
exaly   +2 more sources

Reduced incidence of tick paralysis cases in dogs and cats at two emergency clinics in South‐East Queensland since 2015: new generation prophylactics as possible explanatory variables

Australian Veterinary Journal, Volume 101, Issue 9, Page 356-365, September 2023., 2023
Introduction This study aimed to determine the incidence of canine and feline tick paralysis cases presenting to two veterinary emergency hospitals before and after the introduction of new generation prophylactic acaricides. Methods This was a retrospective study, investigating the number of tick paralysis cases presenting to two emergency and critical
EM Ireland, J Heller, EM Leister, AM Padula   +3 more
wiley   +1 more source

Lotilaner Ophthalmic Solution, 0.25%, for the Treatment of Demodex Blepharitis. [PDF]

Healthcare (Basel)
Demodex blepharitis, a chronic lid margin disease, is caused by an infestation of Demodex mites, the most common ectoparasites in human skin and eyelids. Lotilaner ophthalmic solution, 0.25% (Xdemvy, Tarsus Pharmaceuticals), is the first therapy approved
Davey PG, Farid M, Karpecki P, Gaddie IB, Chan A, Mun J, Neervannan S, Yeu E.   +7 more
europepmc   +2 more sources

Autochthonous Babesia canis infections in 49 dogs in Germany

Journal of Veterinary Internal Medicine, Volume 37, Issue 1, Page 140-149, January/February 2023., 2023
Abstract Background Vector‐borne diseases are of increasing importance in Germany. Since 2015, autochthonous cases have been increasingly documented in Berlin/Brandenburg. Objectives Describe autochthonous Babesia canis infection in the Berlin/Brandenburg region. Animals Forty‐nine dogs with autochthonous B. canis infection.
Christiane Weingart, Christina S. Helm, Elisabeth Müller, Ingo Schäfer, Marianne Skrodzki, Georg von Samson‐Himmelstjerna, Jürgen Krücken, Barbara Kohn   +7 more
wiley   +1 more source

Canine and feline P‐glycoprotein deficiency: What we know and where we need to go

Journal of Veterinary Pharmacology and Therapeutics, Volume 46, Issue 1, Page 1-16, January 2023., 2023
Abstract In 2001 the molecular genetic basis of so‐called “ivermectin sensitivity” in herding breed dogs was determined to be a P‐glycoprotein deficiency caused by a genetic variant of the MDR1 (ABCB1) gene often called “the MDR1 mutation.” We have learned a great deal about P‐glycoprotein's role in drug disposition since that discovery, namely that P ...
Katrina L. Mealey, Jane G. Owens, Elaine Freeman   +2 more
wiley   +1 more source

First Report of Bronchial Oestriasis in a Domestic Dog. [PDF]

Vet Med Sci
Oestrus ovis bronchial myasis is described in a dog for the first time. Bronchoscopy proved essential for larval visualization and removal. Isoxazoline compounds should be considered both as a treatment and as a preventive option. ABSTRACT This study reports the first case of bronchial myiasis in a dog caused by Oestrus ovis, a parasite known to infest
Dini FM, Raponi F, Vallone F, Galuppi R, Macchioni F.   +4 more
europepmc   +2 more sources

Safety of oral afoxolaner formulated with or without milbemycin oxime in homozygous MDR1‐deficient collie dogs

Journal of Veterinary Pharmacology and Therapeutics, Volume 45, Issue 4, Page 373-379, July 2022., 2022
Abstract Afoxolaner, an insecticide and acaricide compound of the isoxazoline class, is available for dogs as an oral ectoparasiticide medicine (NexGard®) and as an oral endectoparasiticide medicine in combination with milbemycin oxime (MO), a macrocyclic lactone (NexGard® Spectra).
Marlene Drag, Eric Tielemans, Elizabeth Mitchell   +2 more
wiley   +1 more source

Molecular Targets of Neurotoxic Insecticides in Apis mellifera

European Journal of Organic Chemistry, Volume 2022, Issue 21, June 7, 2022., 2022
Cloning of the honeybee genes encoding ion channels targeted by neurotoxic insecticides and their functional reconstitution in heterologous expression system allow the assessment of the different insecticide classes including pyrethroids and neonicotinoids. Elucidation of their mode of action, by combining electrophysiology and molecular docking, might
Thierry Cens, Alain Chavanieu, Anaïs Bertaud, Nawfel Mokrane, Sébastien Estaran, Julien Roussel, Claudine Ménard, Marie‐Celeste De Jesus Ferreira, Janique Guiramand, Jean‐Baptiste Thibaud, Catherine Cohen‐Solal, Matthieu Rousset, Valérie Rolland, Michel Vignes, Pierre Charnet   +14 more
wiley   +1 more source

Efficacy of lotilaner (Credelio™) against the adult cat flea, Ctenocephalides felis and flea eggs following oral administration to dogs

Parasites & Vectors, 2020
Background A blinded, randomized, negative controlled laboratory study was conducted to evaluate the efficacy of lotilaner (CredelioTM, Elanco) when administered orally to dogs, against experimentally induced adult flea infestations and flea egg ...
Lisa Young, Daniela Karadzovska, Scott Wiseman, Rainer Helbig   +3 more
doaj   +1 more source