Results 51 to 60 of about 464 (144)

Efficacy of lotilaner (Credelio™) against experimentally induced infestations of the adult cat flea, Ctenocephalides felis, and flea eggs following oral administration to cats

Parasites & Vectors, 2021
Background Credelio™ (lotilaner; Elanco) is indicated for the treatment of flea and tick infestations on cats at a recommended lotilaner dose rate of 6–24 mg/kg.
Tandy Paarlberg, Daniela Karadzovska, Rainer Helbig   +2 more
doaj   +1 more source

Effects of Lotilaner Ophthalmic Solution, 0.25% on <i>Demodex</i> Blepharitis Patients with Meibomian Gland Disease. [PDF]

Clin Ophthalmol
To evaluate the safety and efficacy of lotilaner ophthalmic solution, 0.25% compared with vehicle in Demodex blepharitis patients with meibomian gland disease.This was a pooled analysis of two prospective, randomized, double-masked studies of Demodex blepharitis patients with meibomian gland disease, Ersa (N=39), and Rhea (N=40).
Gupta PK, Gaddie IB, Shultz MC, Vollmer P, Silverstein SM, Shen Lee B, O'Dell L, Dhamdhere K, Yeu E.   +8 more
europepmc   +4 more sources

Milbemycin oxime and lotilaner for heartworm prevention in dogs in Korea: a randomized controlled field trial. [PDF]

J Vet Sci
Heartworm disease can lead to chronic cardiopulmonary complications in dogs, and treatment is often prolonged and costly. In Korea, Dirofilaria immitis, the causative agent of canine heartworm disease, has been reported in both dogs and mosquitoes and is generally considered endemic.This field study evaluated the effectiveness and safety of a ...
Park J, Lee S, Kim C, Min KD, Kim H, Lee SH.   +5 more
europepmc   +3 more sources

Assessment of lotilaner (Credelio® CAT) for control of in-home Ctenocephalides felis infestations. [PDF]

Parasit Vectors
Abstract Background Flea infestations remain a major issue in veterinary medicine. Highly effective flea control for dogs and cats remains the foundation for eliminating infestations from homes and improving skin conditions associated with flea-feeding.
Sutherland C, Tomlinson T, Wilson G, Gray A, Miller K, Gin T, Lashnits E, Li Y, Kollasch TM, Locklear CL, Ryan WG, Canfield M, Herrin BH.   +12 more
europepmc   +4 more sources

Lotilaner is a potent inhibitor of the novel GABA receptor of body lice Pediculus humanus humanus

, 2019
Drug resistance in the parasites field, including the cosmopolitan lice (Pediculus humanus), and the prevalence increasing despite the marketing of new therapies are an important challenge for our societies. The major pharmacological targets of insecticides like pyrethrins, malathion, spinosad and ivermectin (also used as nematicide and acaricide) are ...
Toubate, Berthine, Neveu, Cédric, Debierre-Grockiego, Françoise   +2 more
openaire   +3 more sources

Reduced incidence of tick paralysis cases in dogs and cats at two emergency clinics in South‐East Queensland since 2015: new generation prophylactics as possible explanatory variables

Australian Veterinary Journal, Volume 101, Issue 9, Page 356-365, September 2023., 2023
Introduction This study aimed to determine the incidence of canine and feline tick paralysis cases presenting to two veterinary emergency hospitals before and after the introduction of new generation prophylactic acaricides. Methods This was a retrospective study, investigating the number of tick paralysis cases presenting to two emergency and critical
EM Ireland, J Heller, EM Leister, AM Padula   +3 more
wiley   +1 more source

Efficacy of Credelio Quattro™ (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets) and Credelio™ (lotilaner) chewable tablets in the prevention of Borrelia burgdorferi transmission from infected Ixodes scapularis in dogs. [PDF]

Parasit Vectors
Abstract Background Borrelia burgdorferi , the causative agent of Lyme disease, is a zoonotic vector-borne pathogen transmitted by various Ixodes tick species. Lyme disease, while commonly asymptomatic, can
Anderson W, Savadelis MD, Wiseman S, Mansour A, Maree R, Young L.   +5 more
europepmc   +3 more sources

Autochthonous Babesia canis infections in 49 dogs in Germany

Journal of Veterinary Internal Medicine, Volume 37, Issue 1, Page 140-149, January/February 2023., 2023
Abstract Background Vector‐borne diseases are of increasing importance in Germany. Since 2015, autochthonous cases have been increasingly documented in Berlin/Brandenburg. Objectives Describe autochthonous Babesia canis infection in the Berlin/Brandenburg region. Animals Forty‐nine dogs with autochthonous B. canis infection.
Christiane Weingart, Christina S. Helm, Elisabeth Müller, Ingo Schäfer, Marianne Skrodzki, Georg von Samson‐Himmelstjerna, Jürgen Krücken, Barbara Kohn   +7 more
wiley   +1 more source

Canine and feline P‐glycoprotein deficiency: What we know and where we need to go

Journal of Veterinary Pharmacology and Therapeutics, Volume 46, Issue 1, Page 1-16, January 2023., 2023
Abstract In 2001 the molecular genetic basis of so‐called “ivermectin sensitivity” in herding breed dogs was determined to be a P‐glycoprotein deficiency caused by a genetic variant of the MDR1 (ABCB1) gene often called “the MDR1 mutation.” We have learned a great deal about P‐glycoprotein's role in drug disposition since that discovery, namely that P ...
Katrina L. Mealey, Jane G. Owens, Elaine Freeman   +2 more
wiley   +1 more source

Efficacy of lotilaner (Credelio™) against the adult cat flea, Ctenocephalides felis and flea eggs following oral administration to dogs

Parasites & Vectors, 2020
Background A blinded, randomized, negative controlled laboratory study was conducted to evaluate the efficacy of lotilaner (CredelioTM, Elanco) when administered orally to dogs, against experimentally induced adult flea infestations and flea egg ...
Lisa Young, Daniela Karadzovska, Scott Wiseman, Rainer Helbig   +3 more
doaj   +1 more source