Results 51 to 60 of about 405 (122)

Current review of isoxazoline ectoparasiticides used in veterinary medicine

Journal of Veterinary Pharmacology and Therapeutics, Volume 45, Issue 1, Page 1-15, January 2022., 2022
Abstract The isoxazolines are a novel class of ectoparasiticides with potent inhibitory activity on glutamate‐ and gamma‐aminobutyric acid‐gated chloride channel located in nervous system of invertebrates. In recent years, studies have been performed to evaluate the efficacy and safety of isoxazolines against various types of ectoparasites, including ...
Xueying Zhou, Alexandra E. Hohman, Walter H. Hsu   +2 more
wiley   +1 more source

Functional Characterization of the Cat and Dog Wild-Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany. [PDF]

J Vet Pharmacol Ther
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Siegl L, Bethäuser M, Nürnberger D, Oswald S, Moritz A, Hamann M, Geyer J.   +6 more
europepmc   +2 more sources

Exploring Normal to Abnormal Variations of Grooming Behaviours in Cats. [PDF]

Vet Dermatol
Background: Grooming is a maintenance behaviour accounting for 4% of a cat's activity budget. It consists of several short bouts, and is modified by pruritus and some psychogenic diseases in cats. Objectives: This study aimed to describe cats' grooming behaviour, investigating normal variations in relation to hair length and grooming modifications in ...
Guillon M, Naudin L, Cochet-Faivre N, Titeux E, Gilbert C.   +4 more
europepmc   +2 more sources

The 2023 World Small Animal Veterinary Association (WSAVA)

, 2023
Journal of Small Animal Practice, Volume 64, Issue 12, Page 731-748, December 2023.
P. V. Steagall, L. Pelligand, S. Page, J. L. Granick, F. Allerton, P. M. Bęczkowski, J. S. Weese, A. K. Hrček, F. Queiroga, L. Guardabassi   +9 more
wiley   +1 more source

Efficacy of lotilaner against myiasis caused by Cochliomyia hominivorax (Diptera: Calliphoridae) in naturally infested dogs

Parasites & Vectors, 2023
Background The New World screwworm fly, Cochliomyia hominivorax, is widely distributed across South America. This parasitic insect is a significant cause of primary myiasis in animals, including dogs.
Tássia Lopes do Vale, Alcyjara Rego Costa, Leandro Macedo Miranda, Geovane Ferreira Silva, Naylene Carvalho Sales Silva, Tiago Barbalho Lima, Daniel Praseres Chaves, Heinz Sager, Pedro Veloso Facury Lasmar, Livio Martins Costa–Junior   +9 more
doaj   +1 more source

A randomized, controlled field study to assess the efficacy and safety of lotilaner (Credelio™) in controlling fleas in client-owned cats in Europe

Parasites & Vectors, 2018
Background Lotilaner is a new isoxazoline developed as an oral ectoparasiticide for cats and dogs. Its safety, rapid killing onset of action and sustained speed of fleas and ticks kill for a minimum of one month after administration, were demonstrated in
Daniela Cavalleri, Martin Murphy, Wolfgang Seewald, Steve Nanchen   +3 more
doaj   +1 more source

A randomized, controlled field study to assess the efficacy and safety of lotilaner (Credelio™) in controlling ticks in client-owned cats in Europe

Parasites & Vectors, 2018
Background There is a continuing need for novel approaches to tick infestations treatment and control in cats. Lotilaner, an isoxazoline with rapid onset of action, has proven its efficacy against ticks in laboratory studies.
Daniela Cavalleri, Martin Murphy, Wolfgang Seewald, Steve Nanchen   +3 more
doaj   +1 more source

Survey of canine use and safety of isoxazoline parasiticides

Veterinary Medicine and Science, Volume 6, Issue 4, Page 933-945, November 2020., 2020
A veterinarian and pet owner survey (Project Jake) examined the use and safety of isoxazoline parasiticides given to dogs during August 1‐31, 2018 from 2751 survey responses. When any preventive treatment was given, AE were reported for 66.6% of respondents, with no apparent AE noted for 36.1%.
Valerie Palmieri, W. Jean Dodds, Judy Morgan, Elizabeth Carney, Herbert A. Fritsche, Jaclyn Jeffrey, Rowan Bullock, Jon P. Kimball   +7 more
wiley   +1 more source

Laboratory evaluation of the efficacy and speed of kill of lotilaner (CredelioTM) against Ixodes ricinus ticks on cats

Parasites & Vectors, 2018
Background Lotilaner, approved for dogs as a chewable tablet formulation, has separately been developed for oral use in cats (CredelioTM chewable tablets for cats), to meet the need for an easy to use, safe and rapidly effective parasiticide.
Daniela Cavalleri, Martin Murphy, Wolfgang Seewald, Jason Drake, Steve Nanchen   +4 more
doaj   +1 more source

Laboratory evaluation of the efficacy of lotilaner (Credelio™) against Haemaphysalis longicornis infestations of dogs

Parasites & Vectors, 2018
Background Throughout Japan, Korea and China, Haemaphysalis longicornis ticks are vectors of Babesia gibsoni, which causes severe and progressive anemia in dogs.
Hiroshi Otaki, Junko Sonobe, Martin Murphy, Daniela Cavalleri, Wolfgang Seewald, Jason Drake, Steve Nanchen   +6 more
doaj   +1 more source