Results 71 to 80 of about 405 (122)

Comprehensive evaluation of lifespan‐extending molecules in C. elegans

open access: yesAging Cell, Volume 24, Issue 4, April 2025.
We evaluated 16 of the most frequently reported lifespan‐extending molecules in C. elegans, examining their effects on lifespan with live and UV‐killed OP50. We assessed the compounds' impact on bacterial growth, and their effects on various nematode strains.
Grace B. Phelps   +6 more
wiley   +1 more source

Characterization and Polymorphism Analysis of Lotilaner (CREDELIO) for Flea and Tick Treatment in Dogs [PDF]

open access: yes
CREDELIO (Lotilaner) is a beef-flavored chewable tablet for oral administration to dogs and puppies based on their weight. Each chewable tablet provides a minimum dose of 9 mg of lotilaner per pound of body weight (20 mg/kg)
Anonymous,
core   +1 more source

Prurit et modifications comportementales chez des chats suite à la prise de lotilaner : quel est votre avis ?

open access: yes, 2022
National audienceFortement parasités par des puces, quatre chats adultes de la même famille reçoivent chacun un comprimé de lotilaner.
Laurentie, Sylviane   +1 more
core   +1 more source

Novel drugs approved by the EMA, the FDA, and the MHRA in 2023: A year in review

open access: yesBritish Journal of Pharmacology, Volume 181, Issue 11, Page 1553-1575, June 2024.
Abstract In 2023, seventy novel drugs received market authorization for the first time in either Europe (by the EMA and the MHRA) or in the United States (by the FDA). Confirming a steady recent trend, more than half of these drugs target rare diseases or intractable forms of cancer.
Andreas Papapetropoulos   +16 more
wiley   +1 more source

Field study to investigate the effectiveness and safety of a novel orally administered combination drug product containing milbemycin oxime and lotilaner (Credelio® Plus) against natural intestinal nematode infections in dogs presented as veterinary patients in Europe

open access: yesParasites & Vectors, 2021
Background A randomised, blinded, positive controlled, multicentre, Good Clinical Practice-compliant, pivotal field study was conducted to evaluate the effectiveness and safety of a new combination of lotilaner + milbemycin oxime tablets (Credelio® Plus;
Brad Hayes   +2 more
doaj   +1 more source

Field study to investigate the effectiveness and safety of a novel orally administered combination drug product containing milbemycin oxime and lotilaner (Credelio® Plus) against natural flea and tick infestations on dogs presented as veterinary patients in Europe

open access: yesParasites & Vectors, 2021
Background A pivotal randomised, blinded, positive-controlled, multicentre, European field study was conducted to evaluate the effectiveness and safety of a novel combination tablet of lotilaner and milbemycin oxime (Credelio® Plus) administered orally ...
Sophie Forster   +2 more
doaj   +1 more source

A first insight into the effect of Lotilaner on GABA-gated channels from the european tick Ixodes ricinus

open access: yes, 2019
International audienceTicks are strict blood-feeding arthropods (Acari), which represent a major health issue for wild or domesticated animals and humans, due to their potential to transmit disease agents.
Rispe, Claude   +7 more
core   +4 more sources

Environmental Toxicity Of Isoxazoline Drugs On Non-Target Species [PDF]

open access: yes, 2023
Lyme disease affects tens of thousands of people every year in the United States, causing serious illness and even death. It is caused by the bacterium, Borrelia burgdorferi, through infected black-legged tick bites. The range of these ticks is expanding,
Cooper, Haley M
core   +1 more source

Research progress on ocular surface diseases related to Demodex mite infection

open access: yesYanke Xuebao
Demodex mites are the most common parasites found on human skin. They primarily reside in hair follicles, meibomian glands, and sebaceous glands of the eyes, and can trigger eye-related symptoms such as dry eyes, itchy eyes, and a pronounced foreign-body
ZHANG Xiaoxiao, DING Lin
doaj   +1 more source

Efficacy and innocuity of lotilaner in the treatment of otodectic mange in ferrets

open access: yes
3International audienceOtodectes cynotis is a contagious ear mite generally responsible of a parasitic otitis. This prospective study evaluates the efficacy, safety and impact on quality of life (QoL) of oral lotilaner for the treatment of Otodectes ...
Mardini, D.   +4 more
core   +1 more source

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