Results 61 to 70 of about 405 (122)

Long-term and acute safety of a novel orally administered combination drug product containing milbemycin oxime and lotilaner (Credelio® Plus) in juvenile and adult dogs

Parasites & Vectors, 2021
Background The combination of milbemycin oxime (MO) and lotilaner (Credelio® Plus) is a novel systemic endectocide that provides month-long effectiveness in dogs after a single oral treatment.
Kari L. Riggs, Scott Wiseman
doaj   +1 more source

The <i>Demodex</i> Expert Panel on Treatment and Eyelid Health (DEPTH) Consensus Regarding the Preferred Treatment for <i>Demodex</i> Blepharitis. [PDF]

Clin Ophthalmol
Purpose: To reach consensus on Demodex blepharitis (DB) treatment approaches using a modified Delphi process involving 15 ocular surface disease experts.
Donnenfeld E, Nichols KK, Ayres BD, Farid M, Gupta PK, Lindstrom RL, Pflugfelder S, Starr CE, Venkateswaran N, Gaddie IB, Karpecki PM, Koetting C, McGee S, Periman LM, Yeu E.   +14 more
europepmc   +2 more sources

Centripetal Axonal Transport as a Gateway to the CNS for Veterinary Antiparasitics: Bypassing the Blood–Brain Barrier, Clinical Impact in Vulnerable Age Groups, and the Potential Facilitating Role of PFAS

Journal of Toxicology, Volume 2026, Issue 1, 2026.
The widespread use of veterinary antiparasitics, including neonicotinoids, isoxazolines, avermectins, and pyrethroids, is essential for canine health but raises concerns regarding potential neurotoxicity, particularly in young and geriatric animals.
Domenico Britti, Romano Marabelli, Luigino Calzetta, Harleen Khatra   +3 more
wiley   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

Field study to investigate the effectiveness and safety of a novel orally administered combination drug product containing milbemycin oxime and lotilaner (Credelio® Plus) for the prevention of heartworm disease (Dirofilaria immitis) in client-owned dogs in the USA

Parasites & Vectors, 2021
Background Dirofilaria immitis, a globally distributed filarial parasite of dogs, is known to cause serious or fatal cardiopulmonary disease. Client-owned dogs were enrolled in a clinical field study in the USA to evaluate the clinical effectiveness and ...
Lisa M. Young, Scott Wiseman, Elizabeth Crawley, Kim Wallace, Daniel E. Snyder   +4 more
doaj   +1 more source

Efficacy of a novel chewable tablet (Credelio Quattro^™) containing lotilaner, moxidectin, praziquantel, and pyrantel against Toxocara canis and Toxascaris leonina infections in dogs. [PDF]

Parasit Vectors
Background Roundworms such as Toxascaris leonina and Toxocara canis are routinely diagnosed in dogs globally, especially in dogs 6 months of age or younger.
Charles S, Wiseman S, Wang X, Savadelis MD, Reinemeyer CR, Bouzaidi Cheikhi I, Rautenbach C, Young L.   +7 more
europepmc   +2 more sources

Acaricidal Activity Of The Orally Administered Isoxazoline Drugs (Lotilaner, Fluralaner, And Afoxolaner) In White-Footed Mice Against Larval Ticks [PDF]

, 2023
Lyme disease, caused by Borrelia burgdorferi, is currently the most prevalent vector borne disease in North America. With the CDC estimating almost 500,000 new cases every year, methods are needed to control the vector, the black legged tick (Ixodes ...
Gisi, Emily Marie
core   +1 more source

Safety of lotilaner flavoured chewable tablets (CredelioTM) after oral administration in cats

Parasites & Vectors, 2018
Background Lotilaner is a new member of the isoxazoline class for treatment of flea and tick infestations in cats. This laboratory study with lotilaner vanilla-yeast flavoured chewable tablets (CredelioTM, Elanco) investigated the safety in healthy ...
Emmanuelle A. Kuntz, Srinivas Kammanadiminti   +1 more
doaj   +1 more source

Steroid‐responsive generalised sterile necrotising pyogranulomatous lymphadenitis in a cat

Journal of Small Animal Practice, Volume 66, Issue 9, Page 670-675, September 2025.
A 1.5‐year‐old neutered male cat was presented with fever, inappetence, lethargy and marked generalised lymphadenopathy of 4 days duration. Excisional biopsy of peripheral lymph nodes revealed necrotising pyogranulomatous lymphadenitis. Extensive investigation failed to identify an underlying infectious [bacterial (Bartonella, Mycobacteria, Mycoplasma,
L. Lecot, E. Ramery, M. Hugonnard, A. Tortereau, É. Krafft   +4 more
wiley   +1 more source

Menrath ulcers in cats: four cases (2014‐2023)

Journal of Small Animal Practice, Volume 66, Issue 5, Page 346-352, May 2025.
Objectives To report the clinical presentation, treatment and outcomes of four cats diagnosed with Menrath ulcers causing significant oral haemorrhage. Materials and Methods For all cats, data on signalment, history, physical examination, treatment and outcomes were collected by reviewing medical records.
K. Whybrow, T. Hernon, M. Pilot
wiley   +1 more source