Results 11 to 20 of about 464 (144)
Safety Evaluation of Lotilaner in Dogs After Oral Administration as Flavoured Chewable Tablets (Credelio™) [PDF]
Parasites and Vectors, 2017 Background Lotilaner (Credelio™, Elanco) is a novel isoxazoline that provides rapid speed of flea and tick knockdown which is sustained for at least 1 month following oral administration to dogs.
Emmanuelle A. Kuntz +1 more
exaly +6 more sources
Lotilaner Ophthalmic Solution 0.25%: First Approval [PDF]
Drugs, 2023 Lotilaner ophthalmic solution 0.25% (XDEMVY™), a gamma-aminobutyric acid-gated chloride channel (GABA-Cl) inhibitor selective for mites, is being developed by Tarsus Pharmaceuticals for the treatment of Demodex blepharitis and meibomian gland dysfunction in patients with Demodex lid infestation (Demodex-induced meibomianitis).
Yahiya Y Syed
exaly +5 more sources
The intravenous and oral pharmacokinetics of lotilaner in dogs [PDF]
Parasites & Vectors, 2017 Background Lotilaner is a new oral ectoparasiticide from the isoxazoline class developed for the treatment of flea and tick infestations in dogs. It is formulated as pure S-enantiomer in flavoured chewable tablets (Credelio™).
Céline E. Toutain +2 more
doaj +4 more sources
Assessment of the onset of lotilaner (Credelio™) speed of kill of fleas on dogs [PDF]
Parasites & Vectors, 2017 Background Lotilaner (Credelio™) is the newest member of the novel isoxazoline chemical class to be developed to treat canine ectoparasitism. Administered orally, lotilaner is rapidly absorbed with peak blood levels occurring within 2 h post-treatment. A
Daniela Cavalleri +4 more
doaj +4 more sources
Clinical, Parasitological, and Serological Follow-Up of Dogs with Sarcoptic Mange Treated Orally with Lotilaner [PDF]
Case Reports in Veterinary Medicine, 2021 Canine sarcoptic mange is a highly pruritic and contagious skin disease caused by the mite Sarcoptes scabiei var. canis. This case series describes the clinical, parasitological, and serological follow-up of a cohort of eight adult Saint Bernard dogs ...
F. Moog +3 more
doaj +5 more sources
Laboratory evaluation of the speed of kill of lotilaner (Credelio™) against Ixodes ricinus ticks on dogs [PDF]
Parasites & Vectors, 2017 Background With the geographical expansion of tick species and increased recognition of pathogens they transmit, there is a requirement for safe and rapidly effective control measures for dogs.
Martin Murphy +4 more
doaj +4 more sources
Journal of Ophthalmology, 2021 Purpose. Evaluate safety and efficacy of topical lotilaner ophthalmic solution, 0.25% for the treatment of Demodex blepharitis. Patients and Methods. 15 patients with Demodex blepharitis, defined as >10 collarettes on the upper lid, lid margin erythema ...
Roberto Gonzalez-Salinas +8 more
doaj +3 more sources
Parasites and Vectors, 2017 Background Lotilaner (Credelio™, Elanco), a novel isoxazoline, is a systemic insecticide and acaricide that is rapidly absorbed following oral administration to dogs and has a half-life of 30 days.
Jason Drake +2 more
exaly +4 more sources
PLoS Pathogens, 2021 Control of infestation by cosmopolitan lice (Pediculus humanus) is increasingly difficult due to the transmission of parasites resistant to pediculicides.
Nicolas Lamassiaude +7 more
doaj +6 more sources
Efficacy and Safety of Lotilaner Ophthalmic Solution 0.25% in Demodex Blepharitis: A Systematic Review. [PDF]
HCA Healthc J MedDemodex blepharitis is a chronic eyelid inflammation caused by Demodex mites, which are ubiquitous skin parasites. Lotilaner, a newly United States Food and Drug Administration (FDA)-approved drug, is an antiparasitic agent that selectively inhibits parasite-specific γ-aminobutyric acid chloride channels, inducing spastic paralysis and death of Demodex
Fabara SP, Fabara T, Alok A, Khuddus N.
europepmc +4 more sources