Results 61 to 70 of about 395 (165)

Unveiling the AcSirt2‐FOXO‐Mitophagy Axis: Insights Into Mitochondrial Quality Control and Delayed Aging in Apis cerana

open access: yesAging Cell, Volume 25, Issue 8, August 2026.
Age‐related downregulation of AcSirt2 impairs mitochondrial homeostasis in old bees. AcSirt2‐mediated deacetylation of FOXO enhances transcriptional activity, upregulating antioxidant enzymes (SOD, CAT) and promoting PINK1/Parkin‐mediated mitophagy. This pathway facilitates autophagosome formation and clearance of damaged mitochondria, reducing ROS ...
Qiang Ma   +8 more
wiley   +1 more source

Pomegranate Peel Polyphenol Extract Ameliorates Hyperuricemia by Inhibiting Uric Acid Synthesis and Reabsorption

open access: yesChemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
The graphical abstract illustrates the action mechanisms through which PPE alleviates HUA by inhibiting XOD activity, and by suppressing the PI3K‐AKT signaling pathway to downregulate the expression of the urate reabsorption transporters URAT1 and GLUT9, thereby promoting renal UA excretion and attenuating renal injury.
Zeyu Yin   +6 more
wiley   +1 more source

Creep feed grinding with soft grade wheels. Studies on creep feed grinding. (3rd report)

open access: yesJournal of the Japan Society of Precision Engineering, 1985
Seiki MATSUI   +2 more
openaire   +3 more sources

The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes

open access: yesThe FEBS Journal, Volume 293, Issue 15, Page 4489-4507, August 2026.
Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova   +12 more
wiley   +1 more source

Ettringite Seeds for Strength Enhancement: Novel Synthesis via One‐Step Co‐Precipitation

open access: yesJournal of the American Ceramic Society, Volume 109, Issue 8, August 2026.
ABSTRACT Reduced early strength can be a barrier to the adoption of cements blended with high levels of limestone. Chemical admixtures based on nucleation seeding are emerging as a potential solution. Herein, while synthesis of C‐S‐H‐based seeds has been thoroughly investigated in the literature, there are limited synthesis protocols available on other
Faisal Qadri   +2 more
wiley   +1 more source

Vancomycin Protects Against Lung Injury and Promotes Butyrate Metabolism

open access: yesThe FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Transplanting the fecal microbiota of patients with lung injury into mice causes an increase in LPS in the mice's blood, thereby leading to chronic lung injury in the mice. Meanwhile, oral administration of vancomycin can enhance colonic butyrate metabolism and improve lung injury in mice.
Jianuo Chen   +9 more
wiley   +1 more source

Vibratory Creep Feed Grinding.

open access: yesTRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series C, 1994
Hanasaki, Shinsaku   +3 more
openaire   +2 more sources

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