Results 101 to 110 of about 99,751 (297)
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
Creep of annealed and cold-drawn high-purity copper
William D. Jenkins, T.G. Digges
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Discussion: “Effect of Deoxidation Practice on Creep Strength of Carbon-Molybdenum Steel at 850 and 1000 F” (Miller, R. F., 1943, Trans. ASME, 65, pp. 309–314) [PDF]
Ernest L. Robinson
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Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Closure to “Discussions of ‘Correlation of Tension Creep Test With Relaxation Tests’” (1947, ASME J. Appl. Mech., 14, pp. A352–A355) [PDF]
Egor P. Popov
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TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Discussion: “The Creep of Metals” (Nadai, A., 1933, J. Appl. Mech., 1, pp. 61–76) [PDF]
C. Richard Soderberg
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Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source