Results 141 to 150 of about 99,751 (297)
Molecular Oncology, EarlyView.Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley +1 more source
Modeling of Creep Deformation and Creep Fracture
, 2020 Qiang Xu, Zhongyu Lu
openaire +3 more sources
Creep Compliance of Carbon Black-Filled Rubber Converted from Storage Modulus by Use of Collocation Method: Numerical and Experimental Validation. [PDF]
Polymers (Basel)Zhou B, Zhao B, Tang W, Wang R, Yin B.
europepmc +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Design and development of a novel polymer coating system with exceptional creep resistance. [PDF]
Npj Mater SustainAmeli N +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Study on a Creep Constitutive Model of Phyllite Considering the Coupling Factors of Bedding, Confining Pressure, and Water Saturation. [PDF]
ACS OmegaWu Y, Hu J, Yang D, Wen G.
europepmc +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Compressive Creep Performances of Dispersion Coated Particle Surrogate Fuel Pellets with ZrC-SiC Composite Matrix. [PDF]
Materials (Basel)Ren Q, Liu Y, Fang R, Wu L, Liu W.
europepmc +1 more source
Molecular Oncology, EarlyView.Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan +4 more
wiley +1 more source