A potential tumor suppressor role of PLK2 in glioblastoma
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia+5 more
wiley +1 more source
Study on nonlinear creep damage model based on fractional derivative. [PDF]
Li G, Jia H.
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Discussion: “Critical Examination of Procedures Used in Britain and United States to Determine Creep Stresses for Design of Power Plant for Long Life at High Temperature” (Bailey, R. W., 1954, ASME J. Appl. Mech., 21, pp. 309–322) [PDF]
Ernest L. Robinson
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Identification of inhibitors of the Salmonella FraB deglycase, a drug target
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law+6 more
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Experimental study on the shear creep behavior of residual soil with varying rock content. [PDF]
Wang C+5 more
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Closure to “Discussions of ‘Validity of Time-Compensated Temperature Parameters for Correlating Creep and Creep-Rupture Data’” (1956, Trans. ASME, 78, pp. 1429–1432) [PDF]
F. Garofalo, G. V. Smith, B. W. Royle
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This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma+3 more
wiley +1 more source
Creep Failure Behavior in the Weak Areas of 12Cr1MoV Main Steam Pipe Elbow Utilized in Thermal Power Plants. [PDF]
Wang S, Shi R, Wu J, Yang C, Liu H.
europepmc +1 more source