Results 221 to 230 of about 542,843 (395)

Rational Design of Ionomer Microstructures for Thermally Reprocessable Materials with Creep Resistance and Recoverability. [PDF]

JACS Au
Tsai CC, Fan H, Zhou Y, Xie S.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Impact of fluid creep on volume and chloride load in critically ill adults: a prospective study on its prognostic significance and association with MAKE30. [PDF]

Ren Fail
Zhou D, Cao F, Zhang L, Qiu G, Chen Y, Li Y, Peng Z.   +6 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Effect of reinforcement type and viscoelasticity on static crack growth, fatigue, and creep resistance in acrylonitrile butadiene rubber (NBR) elastomers. [PDF]

Sci Rep
Tavosi S, Alimardani M, Ghoreishy MHR, Tavakol M.   +3 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Linear Viscoelastic Wood Creep Models. [PDF]

Materials (Basel)
Socha T, Kula K, Denisiewicz A.
europepmc   +1 more source

Postseismic relaxation and transient creep [PDF]

, 2005
J. C. Savage, J. L. Svarc, Shui‐Beih Yu   +2 more
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Control techniques for creep deformation of surrounding rock in deep underground roadways. [PDF]

PLoS One
Ge L, Liu D, Tao J, Zhang Z, Lei H, Zhao Y.   +5 more
europepmc   +1 more source