Results 31 to 40 of about 328,728 (301)

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Time-scale effect of the creep model parameters and particle flow simulation of sandstone with a single crack

Yantu gongcheng xuebao, 2019
The creep deformation behaviors of the hard rocks in deep high-stress environment, especially for the fractured hard rocks, cannot be neglected. To investigate the long-term creep deformation behaviors and the creep model for the fractured hard rock, the
HU Bo 1, YANG Sheng-qi 1,2, XU Peng 3, TIAN Wen-ling 1
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Novel direct method on the life prediction of component under high temperature-creep fatigue conditions [PDF]

, 2013
This paper presents a novel direct method, within the Linear Matching Method (LMM) framework, for the direct evaluation of steady state cyclic behaviour of structures subjected to high temperature – creep fatigue conditions.
Chen, Haofeng, Gorash, Yevgen
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Viscoelastic plastic creep constitutive model based on energy conservation law and strain energy theory

Scientific Reports
On the basis of the law of conservation of energy, the three stages of rock creep are analyzed. The reasons for the difficulty in studying the accelerated creep stage of rocks using the traditional creep model are expounded.
Di Zhou, Xiangjin Tian, Shuguang Zhang, Wang Zeng, Minye Zhang, Yanchao Feng, Wenbo Liu, Xiang Huang, Mingzhuo Fan, Ye Sun   +9 more
doaj   +1 more source

Creep behaviour of as received, aged and cold worked INCONEL 617 at 850 °C and 950 °C [PDF]

, 2010
The effect of initial microstructure on alloy 617 creep behaviour has been investigated at 850 °C and 950 °C. The solution treated material shows non-classical creep behaviour at both temperatures with a strain rate drop at the beginning of the tests ...
Chomette, Sébastien, Gentzbittel, Jean-Marie, Viguier, Bernard   +2 more
core   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Microscopic time‐dependent mechanical behavior of shale derived from nanoindentation

Deep Underground Science and Engineering
Understanding the microscopic time‐dependent mechanical behavior of shale is critical for assessing macroscopic creep and engineering applications.
Cunbao Li, Shilei Zhong, Heping Xie, Changtai Zhou, Jianjun Hu   +4 more
doaj   +1 more source

Research on Creep Model of Roadway Surrounding Rock Based on Variable Creep Parameters

Meikuang Anquan, 2020
In order to study the creep behavior of surrounding rock of Huaying Coal Mine in Sichuan under different confining pressure characteristics, the triaxial creep test of sandstone was carried out by TAW-2000 test system.
LIU Changming, ZHANG Hong
doaj   +1 more source