Results 31 to 40 of about 34,050 (268)

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Modeling Full-Stage Rock Creep: A Perzyna Viscoplastic Approach Incorporating Damage and Strain Energy Theory

Geofluids
Under high-level stress, the internal damage of rock accumulates over time, leading to significant nonlinearity in creep. However, traditional linear element combination models struggle to describe the creep behavior of rock in the accelerated creep ...
Xiaolong Zhang, Shutian Zhao, Wenbo Liu, Shuguang Zhang   +3 more
doaj   +1 more source

An elastic-viscoplastic creep model for describing creep behavior of layered rock

Frontiers in Materials, 2023
To describe the full-stage creep behavior of layered rock accurately, a new elastic-viscoplastic creep model is proposed based on fractional order theory in this manuscript, which consists of a Hooke elastomer, a fractional Abel dashpot, a Kelvin body ...
Yukun Li, Mingxuan Shen, Bin Du, Shisong Yuan   +3 more
doaj   +1 more source

From information creep to indication creep

The Journal of Thoracic and Cardiovascular Surgery
No abstract ...
Anselmi, Amedeo, Beurtheret, Sylvain, Barili, Fabio, García-Villarreal, Ovidio A   +3 more
openaire   +2 more sources

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Viscoelastic plastic creep constitutive model based on energy conservation law and strain energy theory

Scientific Reports
On the basis of the law of conservation of energy, the three stages of rock creep are analyzed. The reasons for the difficulty in studying the accelerated creep stage of rocks using the traditional creep model are expounded.
Di Zhou, Xiangjin Tian, Shuguang Zhang, Wang Zeng, Minye Zhang, Yanchao Feng, Wenbo Liu, Xiang Huang, Mingzhuo Fan, Ye Sun   +9 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Microscopic time‐dependent mechanical behavior of shale derived from nanoindentation

Deep Underground Science and Engineering
Understanding the microscopic time‐dependent mechanical behavior of shale is critical for assessing macroscopic creep and engineering applications.
Cunbao Li, Shilei Zhong, Heping Xie, Changtai Zhou, Jianjun Hu   +4 more
doaj   +1 more source

Time-dependentness of Creep Parameter Degradation and Variable Parameter Creep Model

工程科学与技术, 2021
In order to better study the creep properties of rocks under different conditions, the rock triaxial creep tests were conducted using the MTS812.02 test system. Based on the rock rheological mechanics, damage theory and the characteristic analysis of the
Wenbo LIU, Shuguang ZHANG, Boyi SUN
doaj  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source