Results 181 to 190 of about 5,398,452 (282)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Sealing Performance Analysis for the Flange Joint at the Front End of a High-Power Diesel Engine Exhaust Manifold. [PDF]

Materials (Basel)
Hua Q, Ding J, Qin W.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Micromechanical Properties and Deformation Behavior of the Co₇₀Fe₃Mn_3.5Mo_1.5Si₁₁B₁₁ Amorphous Alloy. [PDF]

Materials (Basel)
Pashechko M, Bilyk R, Borc J, Tisov O, Sembratovych N, Kindrachuk M.   +5 more
europepmc   +1 more source

Creep Deformation Characteristics of Weathered Granite

Creep Deformation Characteristics of Weathered Granite
Creep deformation characteristics of weathered granite were studied. While displacement of a structure on foundation rock is the main concern of foundation designers, the mechanical and especially the time dependent properties of weathered granite, which is being used recently as a foundation rock in Japan, have not been investigated so much.
openaire   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Unsteady Creep Damage Model of Rock Considering Acid Solution Corrosion. [PDF]

ACS Omega
Lv H.
europepmc   +1 more source

Characteristics of the high temperature mechanisms of creep and recovery in graphite

, 1962
The research reported in this document has been made possible through the support and sponsorship of the U.S. Department of the Army, through its European Research Office. This report, not necessarily in final form, is intended only for the internal management use of the contractor and the U.S. Department of the Army.
openaire   +4 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Fractional order creep model of thawing sandstone incorporating nuclear magnetic resonance phase transition damage. [PDF]

Sci Rep
Fan K, Li F, Gao X, Bai Y.
europepmc   +1 more source