Results 161 to 170 of about 17,423 (316)
Modelling of masonry creep and damage
, 2005 The problems related to the analysis of ancient constructions are gigantic due to the difficulties in characterizing the geometry, the materials, the sequence of construction, the existing damage and the building processes. A difficult aspect in the repair and strengthening of existing structures is the long-term behaviour of masonry. Safety assessment
Henriques, J. Pina +2 more
openaire +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Creep damage model of deep granite under coupled temperature-stress conditions. [PDF]
Sci RepHu J +8 more
europepmc +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Linear matching method on the evaluation of cyclic behaviour with creep effect
, 2012 This paper describes a new Linear Matching Method (LMM) technique for the direct evaluation of cyclic behaviour with creep effects of structures subjected to a general load condition in the steady cyclic state.
Ure, James Michael +2 more
core
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Evaluation Method for Creep Damage of P92 Steel Based on Magnetic Barkhausen Noise and Magnetoacoustic Emission. [PDF]
Sensors (Basel)Huang Z +5 more
europepmc +1 more source
Effect of the Local Feature on the Damage Growth in Constitutive Equations of Creep and Creep Damage
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 1981 Sumio MURAKAMI, Nobutada OHNO
openaire +2 more sources
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source