Results 221 to 230 of about 13,018 (313)
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Performance Control and Mechanism Analysis of DCLR-Based Composite High-Modulus Asphalt Based on Synergistic Modification Effect. [PDF]
Materials (Basel)Xu B, Yu X, Gao A, Bu G, Lu K.
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum +5 more
wiley +1 more source
Viscoelastic Properties of Porcine Pericardium Under Biaxial Tensile Creep and Stress Relaxation: Application for Novel Aortic Valve Bioprosthesis Design. [PDF]
Bioengineering (Basel)Matjeka E +4 more
europepmc +1 more source
Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy
BMEMat, EarlyView.Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim +5 more
wiley +1 more source
Evaluation Method for Creep Damage of P92 Steel Based on Magnetic Barkhausen Noise and Magnetoacoustic Emission. [PDF]
Sensors (Basel)Huang Z +5 more
europepmc +1 more source
Humans are not unique: difficult birth is common in placental mammals
Biological Reviews, EarlyView.ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley +1 more source
Study on Fatigue Behavior and Life Prediction of Laser Powder Bed Fused Ti6Al4V Alloy at 400 °C. [PDF]
Materials (Basel)Wu L, Xu R, Zhang J, Yu H, Jiao Z.
europepmc +1 more source