Results 121 to 130 of about 715,873 (273)

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang   +18 more
wiley   +1 more source

Creep feeding behaviour of suckling piglets

open access: yes, 2002
Piglets’ growth performance during the suckling period is an important issue for both production and welfare. The suckling piglets are usually supplied with creep food at some time during the suckling period in order to improve their performance before and after weaning. Yet the creep food intake varies between litters and between individuals.
openaire   +1 more source

An Adipocyte MKK3–p38β Axis Preserves Insulin Responsiveness in Mice and Is Reciprocally Altered in Human Obesity

open access: yesAdvanced Science, EarlyView.
The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo   +20 more
wiley   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

open access: yesAdvanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes   +14 more
wiley   +1 more source

The Development and Validation of the Creep Damage Constitutive Equations for P91 Alloy [PDF]

open access: yes
This paper presents research on the validation of a set of creep damage constitutive equations for P91 alloy under multi-axial states of stress, and its applicability under lower stress level.
Yang, Xin, Xu, Qiang, Lu, Zhongyu
core   +2 more sources

Prebiotic galactooligosaccharide improves piglet growth performance and intestinal health associated with alterations of the hindgut microbiota during the peri-weaning period

open access: yesJournal of Animal Science and Biotechnology
Background Weaning stress reduces growth performance and health of young pigs due in part to an abrupt change in diets from highly digestible milk to fibrous plant-based feedstuffs.
Timothy E. Boston   +9 more
doaj   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

open access: yesAdvanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu   +13 more
wiley   +1 more source

Creep feed grinding with soft grade wheels. Studies on creep feed grinding. (3rd report)

open access: yesJournal of the Japan Society of Precision Engineering, 1985
MATSUI, Seiki   +2 more
openaire   +3 more sources

Short- But Not Long-Term Effects of Creep Feeding Provided to Suckling Piglets

open access: yesAnimals
Fifty-eight litters (16 from primiparous gilts and 42 from multiparous sows) were used, with a total number of 750 piglets involved in the study. Birth weight was stratified into three groups: low (1.62 kg; HBW).
María Romero   +9 more
doaj   +1 more source

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