Results 141 to 150 of about 1,563,232 (349)

An Animal‐Free Patient‐Derived Tissue‐Mimetic Biochip Model of the Human Synovial Membrane for Human‐Relevant Osteoarthritis Research

Advanced Healthcare Materials, EarlyView.
Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs, Alexander Stoegner, Mateo G. Vasconez Martínez, Markus M. Schreiner, Melanie Cezanne, Ruth Gruebl‐Barabas, Bettina Rodriguez‐Molina, Juergen Alphonsus, Silvia Hayer, Richard Lass, Iris Gerner, Florien Jenner, Wolfgang Holnthoner, Stefan Toegel, Peter Ertl, Hans P. Kiener, Reinhard Windhager, Mario Rothbauer   +17 more
wiley   +1 more source

Effect of early vs. late maturing sire lines and creep feeding on the cortisol response, intestinal permeability, and growth performance of nursery and finishing pigs. [PDF]

J Anim Sci, 2023
Wensley MR, Woodworth JC, Tokach MD, Goodband RD, DeRouchey JM, Gebhardt JT.   +5 more
europepmc   +1 more source

Forma física da ração e pesos de abate nas características de carcaça de cordeiros em creep feeding [PDF]

, 2001
Marcela Abbado Neres, Alda Lúcia Gomes Monteiro, Clédson Augusto Garcia, Ciniro Costa, Mário De Beni Arrigoni, Guilherme J. M. Rosa   +5 more
openalex   +1 more source

Enhancing the Pharmacokinetics of Aptamers: Targeting AXL In Vivo Using a Bottlebrush Polymer‐Conjugated Aptamer

Advanced Healthcare Materials, EarlyView.
A phosphodiester‐backboned bottlebrush polymer (pacDNA) engineered for aptamer delivery is presented. This design enhances aptamer stability, plasma pharmacokinetics, and target engagement in vivo. In AXL‐driven cancer models, pacDNA inhibits AXL signaling and reduces tumor growth, highlighting the promise of precision polymer scaffolds in aptamer ...
Tingyu Sun, Jiachen Lin, Chenyang Xue, Yuyan Wang, Peiru Chen, Yun Wei, Guobin Xu, Anais Sidonia, Chris Nenopoulos, Hossam Tashkandi, Caroline Shen, Allison Wang, Alex Wang, Ke Zhang   +13 more
wiley   +1 more source

Medidas objetivas e composição tecidual da carcaça de cordeiros alimentados com diferentes níveis de energia em creep feeding [PDF]

, 2003
Clédson Augusto Garcia, Alda Lúcia Gomes Monteiro, Ciniro Costa, Marcela Abbado Neres, Guilherme J. M. Rosa   +4 more
openalex   +1 more source

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Qualidade da carne de cordeiros criados em creep feeding com silagem de grãos úmidos de milho [PDF]

, 2004
Gercílio Alves de Almeida Júnior, Ciniro Costa, Alda Lúcia Gomes Monteiro, Clédson Augusto Garcia, Danísio Prado Munari, Marcela Abbado Neres   +5 more
openalex   +1 more source

Baby Pigs [PDF]

, 1943
PDF pages:
Davidson, Howard
core  

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Effect of Feeding Probiotics and Milk Powder Supplemented Creep Ration on the Blood Profile of Pre-Weaned Hampshire Piglets [PDF]

, 2020
Monica Tissopi, J.P. Bordoloi, Anubha Baruah, Jakir Hussain, Rajib Kro   +4 more
openalex   +1 more source