Results 61 to 70 of about 1,563,232 (349)
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
Quarenta cordeiros mestiços "Texel" oriundos de partos simples foram distribuídos em quatro tratamentos, para se comparar o desempenho dos animais terminados a pasto, com e sem suplementação, e em confinamento.
José Reinaldo de Amorim Bernardi+2 more
doaj +1 more source
This experiment compared growth, physiological, and reproductive responses of beef heifers with (MI) or without (CON) access to a creep-feeder, as a manner to stimulate metabolic imprinting while nursing their dams.
M. M. Reis+10 more
semanticscholar +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Surface movement and cascade processes on debris cones in temperate high mountain (Picos de Europa, northern Spain) [PDF]
Producción CientíficaDebris talus is a very common landform in the temperate high mountain, so much so that it is the most representative of the periglacial and nival processes.
Gómez Gutiérrez, Álvaro+3 more
core +2 more sources
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban+12 more
wiley +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian+6 more
wiley +1 more source
Avaliou-se o efeito da suplementação de bezerros em sistema de creep feeding, em pastagens de Brachiaria brizantha, durante o período de amamentação, sobre o ganho médio diário (GMD), peso à desmama (PD) e taxa de gestação, em delineamento inteiramente ...
E. Nogueira+5 more
doaj +1 more source
Organic Pig Production in Europe - Health Management in Common Organic Pig Farming [PDF]
Organic farmers in Europe have developed different housing systems for pigs based on the availability of land, soil characteristics, climate, tradition and national organic certification schemes.
Bochicchio, Davide+8 more
core +1 more source