Results 41 to 50 of about 20,345 (260)

Modeling Full-Stage Rock Creep: A Perzyna Viscoplastic Approach Incorporating Damage and Strain Energy Theory

Geofluids
Under high-level stress, the internal damage of rock accumulates over time, leading to significant nonlinearity in creep. However, traditional linear element combination models struggle to describe the creep behavior of rock in the accelerated creep ...
Xiaolong Zhang, Shutian Zhao, Wenbo Liu, Shuguang Zhang   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Study on Creep Characteristics and Constitutive Relation of Fractured Rock Mass

Shock and Vibration, 2020
In order to effectively describe the whole creep process of fractured rock mass, triaxial unloading creep tests were carried out on prefractured coal samples using constant axial pressure and graded unloading confining pressure, and the axial and lateral
Maotong Li, Kesheng Li, Deng Zhang, Chuanxiao Liu, Depeng Ma   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Viscoelastic plastic creep constitutive model based on energy conservation law and strain energy theory

Scientific Reports
On the basis of the law of conservation of energy, the three stages of rock creep are analyzed. The reasons for the difficulty in studying the accelerated creep stage of rocks using the traditional creep model are expounded.
Di Zhou, Xiangjin Tian, Shuguang Zhang, Wang Zeng, Minye Zhang, Yanchao Feng, Wenbo Liu, Xiang Huang, Mingzhuo Fan, Ye Sun   +9 more
doaj   +1 more source

Creep behaviors and constitutive model of transversely isotropic rocks

Yantu gongcheng xuebao, 2018
The bedded carbonaceous slate exhibits transversely isotropic creep properties. The creep behaviors of carbonaceous slate are studied using the triaxial compressive creep tests on horizontal bedding specimens and vertical bedding specimens.
WANG Zhe-chao 1, 2, ZONG Zhi 1, QIAO Li-ping 1, 2, LI Wei1, LIU Jie 1
doaj   +1 more source

A Fractional Order Creep Damage Model for Microbially Improved Expansive Soils

Frontiers in Earth Science, 2022
Microbial Induced Calcite Precipitation method was used to improve the expansive soils of Nanning, Guangxi. The nonlinear shear creep behavior of microbially improved expansive soil was studied by triaxial consolidation drainage shear test.
Tian Xuwen, Xiao Hongbin, Li Zhenyu, Su Hunayu, Ouyang Qianwen, Luo Shenping, Yu Xinpei   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Creep constitutive model of strain energy density considering the whole process of creep deformation.

PLoS ONE
Aiming at the problem that the traditional creep model is difficult to reflect the characteristics of accelerated creep stage of rock, the influence of stress state on accelerated creep is fully considered, and a constitutive model which can describe ...
Yuemei Li
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source