Results 61 to 70 of about 191,694 (304)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Nonlinear Viscoelastic-Plastic Creep Model of Rock Based on Fractional Calculus

Advances in Civil Engineering, 2022
A rock creep constitutive model is the core content of rock rheological mechanics theory and is of great significance for studying the long-term stability of engineering.
Erjian Wei, Bin Hu, Jing Li, Kai Cui, Zhen Zhang, Aneng Cui, Liyao Ma   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Study on the Allowable Exposure Time of Temporary Goaf in the Open Stope and Backfill Mining Method with Large Structure Parameters

Advances in Civil Engineering, 2020
Based on the uniaxial rheological experiment data of iron ore rock mass and filling body in large-scale stope obtained by using the rock servo controlling creep equipment, the characteristics of the creep curve were analyzed. The creep models of iron ore
Xiaosheng Liu, Weijun Wang, Yizhong Luo, Jin Zhan   +3 more
doaj   +1 more source

Enhancement of critical current density and vortex activation energy in proton-irradiated Co-doped BaFe2As2

, 2012
The effect of proton irradiation in Ba(Fe0.93Co0.07)2As2 single crystals is reported. We analyze temperature dependence of current density and normalized flux relaxation rate in the framework of collective creep model.
Kitamura, Hisashi, Nakajima, Yasuyuki, Taen, Toshihiro, Tamegai, Tsuyoshi   +3 more
core   +1 more source

Creep and Fracture in Concrete: A Fractional Order Rate Approach [PDF]

, 2002
The paper analyses the interaction between strain-softening and time-dependent behaviour in the case of quasi-static fracture of concrete. A viscous element based on a fractional order rate law is coupled with a micromecanical model for the fracture ...
Barenblatt, Barpi, Barpi, Bažant, Bocca, Carpinteri, Carpinteri, Carpinteri, Dugdale, Enelund, F. Barpi, Hillerborg, Huang, Karihaloo, Oldham, S. Valente, Santhikumar, Santhikumar   +17 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Continuum modeling of mechanically-induced creep in dense granular materials

, 2014
Recently, a new nonlocal granular rheology was successfully used to predict steady granular flows, including grain-size-dependent shear features, in a wide variety of flow configurations, including all variations of the split-bottom cell.
Henann, David, Kamrin, Ken
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source