Results 81 to 90 of about 191,694 (304)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Research on Unsteady Burgers Creep Constitutive Model and Secondary Development Application
Applied SciencesConsidering the complexity and diversity of water-rich soft soil strata, indoor triaxial shear tests and creep tests were conducted on soft soil to explore its deformation law and creep characteristics.
Ruonan Zhu +4 more
doaj +1 more source
Quantum creep and quantum creep transitions in 1D sine-Gordan chains
, 2003 Discrete sine-Gordon (SG) chains are studied with path-integral molecular dynamics. Chains commensurate with the substrate show the transition from collective quantum creep to pinning at bead masses slightly larger than those predicted from the ...
E. K. Sklyanin +10 more
core +1 more source
A re-assessment of elastic follow-up in high temperature piping [PDF]
, 2012 The problem of elastic follow‐up in high temperature piping has a long (and interesting) history. Until a paper by Robinson1 in 1955 it was assumed that since the piping was ‘deformation controlled’, the strain would remain broadly constant with the ...
Boyle, James
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Simulation of the small punch creep test with consideration of variation of material properties [PDF]
, 2009 A new finite element model of the small punch creep test is described. The material constitutive relationship for creep considered is a simple Norton power law: in this study the exponent in the power law is varied for each element to simulate the random
Boyle, J., Mackenzie, D., Pan, W.
core
Probing polymer chain constraint and synergistic effects in nylon 6-clay nanocomposites and nylon 6-silica flake sub-micro composites with nanomechanics [PDF]
, 2015 In this study, we report that a synergistic effect exists in the surface mechanical properties of nylon 6–clay nanocomposites (NC) that can be shown by nanomechanical testing.
Beake, BD +4 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Some consequences of stress range dependent constitutive models in creep [PDF]
, 2010 Studies of the behaviour of structural components at high temperature subject to creep have a long history and their behavioural characteristics, certainly for constant and cyclic load, well established.
Boyle, James
core
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source