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Fractional Derivative Creep Model of Salt Rock

open access: yes工程科学与技术, 2014
:The creep property of the salt rock is an important determinant of deep underground repository of energy for long-term operation.New fractional derivative creep model was built by using the Abel dashpot and Abel dashpot with strain triggered based on ...
吴斐, 刘建锋, 边宇, 周志威
doaj  

Creep damage constitutive model of rock based on the mechanisms of crack-initiated damage and extended damage

open access: yesUnderground Space
Since the classical element model cannot describe the nonlinear characteristics of rock during the entire compressive creep process, nonlinear elements and creep damage are generally introduced in the model to resolve this issue.
Tianbin Li   +5 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

A Chemical Damage Creep Model of Rock Considering the Influence of Triaxial Stress. [PDF]

open access: yesMaterials (Basel), 2022
Chen Y   +7 more
europepmc   +1 more source

Modeling ratchet growth as porosity creep

open access: yesInternational Journal Of Chemistry, Mathematics And Physics, 2020
Irreversible thermal cycling growth (or ratchet growth) of insensitive explosive formulations has been known for years. Traditionally it’s attributed to material texture and to anisotropic thermal expansion. Although this understanding has been accepted for a long time, we’re not aware of any model on the macroscale that connects these material ...
openaire   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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