Results 111 to 120 of about 20,345 (260)
An Improved Mechanistic-Empirical Creep Model for Unsaturated Soft and Stabilized Soils. [PDF]
Materials (Basel), 2021 Jiang X, Huang Z, Luo X.
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
StudyonCreepPropertiesandConstitutiveModelofThenardite
工程科学与技术, 2015 :To study creep properties of thenardite,triaxial compression creep tests to thenardite specimens were carried out on the RLW-2000 rock rheology testing machine.The test results indicated that the creep strain and steady creep rate of thenardite ...
王军保 +3 more
doaj
Scientific ReportsMuddy siltstone combines the characteristics of both sandstone and mudstone, and is prone to instability over time. To study the long-term stability of tunnel engineering in this stratum, this article taking the cross-river metro tunnel section as the ...
Huijuan Deng +5 more
doaj +1 more source
A Nonlinear Fractional Viscoelastic-Plastic Creep Model of Asphalt Mixture. [PDF]
Polymers (Basel), 2021 Zhang Y, Liu X, Yin B, Luo W.
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A novel nonlinear creep model based on damage characteristics of mudstone strength parameters. [PDF]
PLoS One, 2021 Hu B, Cui A, Cui K, Liu Y, Li J.
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Applied SciencesRock creep commonly appears in rock mass engineering, and it should be paid appropriate attention. In this paper, studies on creep constitutive models of rocks were reviewed, and it was found that the types of creep constitutive models can generally be ...
Pingyang Fan +6 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source