Results 101 to 110 of about 20,345 (260)

Influence of Temperature, Humidity and Load Coupling on Mechanical Properties of Adhesive Joints and Establishment of Creep Model. [PDF]

Polymers (Basel), 2023
Tan W, Zhou Z, Na J, Mu W.
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Anisotropic time-dependent behaviors of shale under direct shearing and associated empirical creep models

Journal of Rock Mechanics and Geotechnical Engineering
Understanding the anisotropic creep behaviors of shale under direct shearing is a challenging issue. In this context, we conducted shear-creep and steady-creep tests on shale with five bedding orientations (i.e.
Yachen Xie, Michael Z. Hou, Hejuan Liu, Cunbao Li   +3 more
doaj   +1 more source

Fuzzy random evaluation of creep model of frozen soft soil in metro tunnel construction using artificial ground freezing technique. [PDF]

Sci Rep, 2023
Yao Y, Zhu Y, Shen D, Zhang Z, Wang W.
europepmc   +1 more source

Fractal Continuum Maxwell Creep Model

Axioms
In this work, the fractal continuum Maxwell law for the creep phenomenon is introduced. By mapping standard integer space-time into fractal continuum space-time using the well-known Balankin’s approach to variable-order fractal calculus, the fractal version of Maxwell model is developed.
Andriy Kryvko, Claudia C. Gutierrez-Torres, José Alfredo Jiménez-Bernal, Orlando Susarrey-Huerta, Eduardo Reyes de Luna, Didier Samayoa-Ochoa   +5 more
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Research on Creep Constitutive Model for High Temperature Reactor Based on Neural Network

Yuanzineng kexue jishu
This research aims to develop a novel creep constitutive model, leveraging neural networks to precisely predict long-term creep behavior from short-term data.
ZHANG Fan, DAI Shoutong
doaj   +1 more source

A Phenomenological Primary-Secondary-Tertiary Creep Model for Polymer-Bonded Composite Materials. [PDF]

Polymers (Basel), 2021
Duan X, Yuan H, Tang W, He J, Guan X.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Energy-based nonlinear damage creep model considering the influence of the concrete creep rate

Frontiers in Materials
In order to study the influence of confining pressure on the deformation of concrete, triaxial compression and creep tests under different confining pressures are carried out using a combination of laboratory tests and theoretical analysis.
Lu Wang
doaj   +1 more source