Results 51 to 60 of about 11,846 (230)

Syphilis-related rapidly progressive glomerulonephritis: a case presentation

open access: yesBMC Nephrology, 2021
Background Syphilis is a multisystemic infection that causes a wide variety of symptoms and thus has been dubbed one of the great medical mimickers.
A. Qi, P. O. Fiset, L. Pilozzi-Edmonds
doaj   +1 more source

Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus

open access: yesAdvanced Science, EarlyView.
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu   +10 more
wiley   +1 more source

The role of mammalian target of rapamycin pathway in the pathogenesis of pauci-immune glomerulonephritis

open access: yesRenal Failure, 2019
Background: The characteristic lesion of pauci-immune glomerulonephritis is focal necrotizing and crescentic glomerulonephritis. The underlying mechanisms in the formation or progression of crescent formation need further investigations.
Zeki Soypacaci   +7 more
doaj   +1 more source

Gremlin, a potential urinary biomarker of anca-associated crescentic glomerulonephritis [PDF]

open access: yes, 2019
Gremlin renal overexpression has been reported in diabetic nephropathy, pauci-immune crescentic glomerulonephritis and chronic allograft nephropathy and has been implicated in the pathophysiology of the progression of renal damage. However, it is unknown
Burgos, María E.   +7 more
core   +2 more sources

Establishment of a mouse model of propylthiouracil‐induced antineutrophil cytoplasmic antibody‐associated vasculitis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This graphical abstract summarizes our study in which we established a novel murine model of antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis. Neutrophil recruitment was induced using thioglycolate, followed by timed administration of propylthiouracil and phorbol 12‐myristate 13‐acetate to generate DNase I‐resistant neutrophil ...
Sakiko Masuda   +9 more
wiley   +1 more source

The research progress of podocytes in crescentic glomerulonephritis

open access: yesLinchuang shenzangbing zazhi, 2020
Crescentic glomerulonephritis(GN)clinically manifests as acute glomerulonephritis syndrome,and is a common acute critical disease in the area of kidney diseases.Its pathology is characterized by formation of more than 50% of glomerular crescents in the ...
ZOU Rong, HU Tao-tao, YU Bing-zhi
doaj  

Scleroderma with crescentic glomerulonephritis: a case report

open access: yesJournal of Medical Case Reports, 2008
Introduction Systemic sclerosis or scleroderma is an autoimmune rheumatic disease characterized by organ-based fibrosis. Renal involvement in scleroderma occurs mainly in the form of scleroderma renal crisis, affecting 5 to 10% of patients.
Ramaswami Arunachalam   +8 more
doaj   +1 more source

Glucocorticoids target the CXCL9/CXCL10-CXCR3 axis and confer protection against immune-mediated kidney injury

open access: yesJCI Insight, 2023
Glucocorticoids remain a cornerstone of therapeutic regimes for autoimmune and chronic inflammatory diseases — for example, in different forms of crescentic glomerulonephritis — because of their rapid antiinflammatory effects, low cost, and wide ...
Jan-Hendrik Riedel   +18 more
doaj   +1 more source

Modulators of crescentic glomerulonephritis. [PDF]

open access: yesJournal of the American Society of Nephrology, 1996
Glomerular crescent formation is a prominent feature of aggressive forms of glomerulonephritis and is associated with a poor prognosis. An understanding of the mechanisms involved in crescent formation is crucial for the development of new therapies for this disease.
R C, Atkins   +3 more
openaire   +2 more sources

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