Results 61 to 70 of about 11,949 (227)

Assessment of some cytokines levels in a pauci-immune crescentic glomerulonephritis patients

open access: yesKufa Journal for Nursing Sciences, 2023
Background: Glomerulonephritis is the common cause of end-stage of renal failure. Rapidly progressive glomerulonephritis (RPGN) is characterized by glomerular injuries and formation of crescents.  Moreover, anti-neutrophil cytoplasmic antibodies (ANCA),
Dina A. A. Al-Roubaey   +4 more
doaj   +1 more source

PLA2R‐Positive Membranous Nephropathy and AA Amyloidosis in an Ethiopian Patient With Chronic Hepatitis B: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT The coexistence of primary phospholipase A2 receptor positive membranous nephropathy and AA amyloidosis in a patient with chronic hepatitis B is an exceedingly rare triad presenting a profound diagnostic and therapeutic challenge. A 38‐year‐old Ethiopian man with nephrotic syndrome and chronic hepatitis B had dual pathology on renal biopsy ...
Betelhem Abreham   +4 more
wiley   +1 more source

Churg-Strauss Syndrome with Necrosis of Toe Tips [PDF]

open access: yes, 2011
Churg-Strauss syndrome (CSS) is a granulomatous necrotizing vasculitis of unknown etiology associated with bronchial asthma. Despite affecting small to medium-sized vessels, necrosis of the digits due to vasculitis is extremely rare.
Hasegawa, Kenjiro   +9 more
core   +1 more source

Predicting Macrophage Spatial Localization from Single‐Cell Transcriptomes to Uncover Disease Mechanisms

open access: yesAdvanced Science, Volume 13, Issue 21, 13 April 2026.
This study presents a machine‐learning framework entitled MERLIN that infers the microanatomical localization of macrophages from single‐cell transcriptomic data in structured organs such as the kidney and brain. Applying this method to existing datasets from models of acute kidney injury and diabetic nephropathy uncovered spatially resolved insights ...
Junping Yin   +18 more
wiley   +1 more source

Annexin A1 exerts renoprotective effects in experimental crescentic glomerulonephritis

open access: yesFrontiers in Physiology, 2022
Non-resolving inflammation plays a critical role during the transition from renal injury towards end-stage renal disease. The glucocorticoid-inducible protein annexin A1 has been shown to function as key regulator in the resolution phase of inflammation,
Robert Labes   +6 more
doaj   +1 more source

Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus

open access: yesAdvanced Science, Volume 13, Issue 24, 27 April 2026.
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu   +10 more
wiley   +1 more source

A rare case of renal thrombotic microangiopathy associated with Castleman’s disease [PDF]

open access: yes, 2017
BACKGROUND: Castleman’s disease (CD) is an uncommon, heterogeneous lympho-proliferative disorder leading to high circulating levels of interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF).
Chen, Ying Maggie   +3 more
core   +2 more sources

Identification of Histone Deacetylase Inhibitor Targeting Type I Interferon and B Cell Abnormalities in Systemic Lupus Erythematosus

open access: yesArthritis &Rheumatology, Volume 78, Issue 4, Page 880-895, April 2026.
Objective Systemic lupus erythematosus (SLE) is characterized by increased Type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama   +16 more
wiley   +1 more source

Retrospective Analysis of the Cases Diagnosed With Rapidly Progressive Glomerulonephitis

open access: yesTurkish Journal of Nephrology, 2019
AIM: In the present study, we investigated clinical and histopathological findings, treatment, and course of patients with crescentic glomerulonephritis in our center.
Aydın ÜNAL   +6 more
doaj  

The role of Th1 and Th17 cells in glomerulonephritis. [PDF]

open access: yes, 2015
CONTEXT T helper (Th) cells as an important part of the immune is responsible for elimination of invading pathogens. But, if Th cell responses are not regulated effectively, the autoimmune diseases might develop.
Azadegan-Dehkordi, Fatemeh.   +3 more
core   +2 more sources

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