Results 81 to 90 of about 11,949 (227)

Associação de doença do anticorpo anti-membrana basal glomerular com dermatomiosite e psoríase: relato de caso [PDF]

, 2010
CONTEXT: Anti-glomerular basement membrane (anti-GBM) antibody syndrome is characterized by deposition of anti-GBM antibodies on affected tissues, associated with glomerulonephritis and/or pulmonary involvement.
Buosi, Ana Letícia Pirozzi, Camargo, Cintia Zumstein, Machado, Natália Pereira, Oliveira, Ana Cecília Diniz, Pucinelli, Mário Luiz Cardoso, Souza, Alexandre Wagner Silva de   +5 more
core   +2 more sources

Unveiling the immune landscape and microenvironmental architecture of IgA nephropathy using single‐cell imaging mass cytometry

Clinical &Translational Immunology, Volume 15, Issue 3, 2026.
In IgA nephropathy (IgAN), innate and adaptive immune cells display distinct spatial compartmentalisation, with macrophages predominating within glomeruli and CD4+ T cells constituting the major immune population in inflammatory foci. Glomeruli with distinct pathological morphologies exhibit morphology‐dependent immune infiltration patterns and ...
Xing Chen, Long Liu, Lijing Yao, Jianxin Shen, Hengyuan Zhang, Leping Shao, Xingxing Yu, Zhijuan Lin, Lu Zhang   +8 more
wiley   +1 more source

Clinic manifestations in granulomatosis with polyangiitis [PDF]

, 2016
Granulomatosis with polyangiitis (GPA), formerly Wegener's granulomatosis (WG), is an uncommon immunologically mediated systemic small-vessel vasculitis that is pathologically characterised by an inflammatory reaction pattern (necrosis, granulomatous ...
De Vincentiis, Marco, De Virgilio, Armando, Fusconi, Massimo, Gallo, Andrea, Greco, Antonio, Macri, Gian Franco, Marinelli, Caterina, Zambetti, Giampietro   +7 more
core   +1 more source

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

Pediatric Blood &Cancer, Volume 73, Issue 5, May 2026.
Gabriele Mortari, Caterina Costagliola, Marta Nebiolo, Francesca Parisi, Martina Morini, Katia Mazzocco, Gabriele Gaggero, Stefano Volpi, Stefania Sorrentino, Virginia Livellara   +9 more
wiley   +1 more source

Piezo1‐Mediated Mechanotransduction: Orchestrating the Dynamic Response of Podocytes and Parietal Epithelial Cells to Mechanical Stress

Acta Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim The glomerulus is a specialized microvascular unit that filters plasma through the coordinated function of podocytes and parietal epithelial cells (PECs). From this perspective, the glomerulus functions like a living hydrogeological filtration system.
Maria Elena Melica, Giulia Antonelli, Anna Julie Peired, Laura Lasagni   +3 more
wiley   +1 more source

Clinical characteristics and short term outcomes of childhood immune complex membranoproliferative glomerulonephritis and C3 glomerulopathy: a single centre retrospective study

BMC Nephrology
Background Membranoproliferative glomerulonephritis, with its immune complex variety and C3 glomerulopathy, is a rare glomerular disease in children. The objective of this study was to determine the clinical features and short-term outcomes in children ...
Irshad Ali Bajeer, Sabeeta Khatri, Pawan Kumar, Seema Hashmi, Mohammed Mubarak, Ali Asghar Lanewala   +5 more
doaj   +1 more source

Crescentic glomerulonephritis with anti-GBM antibody but no glomerular deposition

BMC Nephrology, 2018
Background Anti-glomerular basement membrane (GBM) antibodies are highly specific for Goodpasture’s or anti-GBM disease, in which they are generally directed against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen(α3(IV)), and ...
Omid Sadeghi-Alavijeh, Scott Henderson, Paul Bass, Terence Cook, Kirsten DeGroot, Alan David Salama   +5 more
doaj   +1 more source

Differences in the frequency of macrophage and t cell markers between focal and crescentic classes of antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis [PDF]

, 2017
Funding/Support This study was supported by Tenovus Scotland/Tayside grant award to DK (Grant # T13/15).Peer reviewedPublisher ...
Bray, Susan E., Fleming, Stewart, Kidder, Dana   +2 more
core   +5 more sources

The Complement System in ANCA‐Associated Vasculitis: Mechanistic Insights, Therapeutic Horizons, and Unmet Clinical Needs

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
Complement activation, particularly via the alternative pathway, drives inflammation and organ damage in ANCA‐associated vasculitis. This review highlights mechanistic insights, tissue and biomarker evidence, and clinical implications of targeting the C5a–C5aR1 axis.
Kehinde Sunmboye, Pauline Millan
wiley   +1 more source

A Case of Henoch-Schonlein Purpura Associated with Rotavirus Infection in an Elderly Asian Male and Review of the Literature. [PDF]

, 2017
BACKGROUND Henoch-Schönlein purpura (HSP), a small vessel vasculitis mediated by deposition of immune-complexes containing IgA in the skin, gut, and glomeruli, often presents with abdominal pain, purpuric rash in the lower extremities and buttocks, joint
Adderley, Adderley, Bender, Epstein, Homberg, Kim, Mongillo, Page, Raja Beharelle, Ridding, Saur, Szaflarski, Wade, Zaccolo   +13 more
core   +2 more sources