Results 41 to 50 of about 1,842 (167)

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

Food Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao, Jiayao Wang, Yilian Huang, Na Zhang, Xiaodan Shi, Zongcai Tu, Zuohua Xie, Tao Yuan, Hongmei Yin   +8 more
wiley   +1 more source

Imidazole-rich copper peptides as catalysts in xenobiotic degradation.

PLoS ONE, 2020
Laccases, oxidative copper-enzymes found in fungi and bacteria were used as the basis in the design of nona- and tetrapeptides. Laccases are known to be excellent catalysts for the degradation of phenolic xenobiotic waste.
Sharifa Zaithun Begum, Nurul Shairah Mohd Nizam, Azira Muhamad, Mohd Izham Saiman, Karen Anne Crouse, Mohd Basyaruddin Abdul Rahman   +5 more
doaj   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source

Odorants in Fish Feeds: A Potential Source of Malodors in Aquaculture

Frontiers in Chemistry, 2018
Although the microbiota is considered to be the primary source of off-flavors in farmed fish, there is a lack of information about the possible contribution of feeds to fish malodor.
Mohamed A. A. Mahmoud, Mohamed A. A. Mahmoud, Mohamed A. A. Mahmoud, Thorsten Tybussek, Helene M. Loos, Helene M. Loos, Maria Wagenstaller, Andrea Buettner, Andrea Buettner   +8 more
doaj   +1 more source

Ocean acidification at the crossroads I: Harmonizing unpurified and purified meta‐cresol purple spectrophotometric pHT measurements based on absorbance data

Limnology and Oceanography: Methods, EarlyView.
Abstract Consistent monitoring of seawater spectrophotometric pH on the total hydrogen ion scale (pHT) has been questioned by an evolving method, with changes in parameterization and the purity of the meta‐cresol purple (mCP). Using real seawater samples, we demonstrate that spectrophotometric pHT measurements obtained with unpurified (UNPUR) and ...
Marta Álvarez, Maribel I. García‐Ibáñez, Rubén Acerbi, Rocío Santiago‐Domenech, Elisa F. Guallart, Noelia M. Fajar, Lisandro Arbilla   +6 more
wiley   +1 more source

Redox‐Active and Electrochromic Aromatic Poly(Ether‐Imide)s With Carbazole‐Triphenylamine Chromophores

Journal of Polymer Science, EarlyView.
A novel ether‐bridged dianhydride monomer based on a carbazole‐triphenylamine (CzTPA) unit has been successfully synthesized, resulting in the development of electroactive and electrochromic poly(ether imide)s that incorporate CzTPA chromophores within the polymer chain.
Wen‐Xuan Chen, Sheng‐Huei Hsiao
wiley   +1 more source

Development of a Novel Polyleucine‐Based Immunopotentiator for Subunit Vaccines Against Group A Streptococcus

Small, EarlyView.
Self‐assembling amphiphilic peptide L15K6 is used as a novel immunoadjuvant for the development of a Group A Streptococcus vaccine. Robust antigen‐specific IgG responses are generated and manage to kill isolated strains of Group A Streptococcus. Cellular and bulk RNA sequencing data reveals that L15K6 regulates immune responses potentially through TLR ...
Lantian Lu, Jazmina L. Gonzalez Cruz, Rabina Giri, Yuexiao Zhang, Sahra Bashiri, Leslie C. Domínguez Cadena, Shuhang Li, Zeinab G. Khalil, Waleed M. Hussein, Jingwen Wang, Jolynn Kiong, Xuehan Lu, Jiahui Zhang, Miao Lu, Wenbin Huang, Wei Yang Kong, Ummey Jannatun Nahar, Prashamsa Koirala, Zhong Guo, Patricia Walden, Antje Blumenthal, Jakob Begun, Kirill Alexandrov, Istvan Toth, Rachel J. Stephenson, Mariusz Skwarczynski   +25 more
wiley   +1 more source

Pollination‐related plant traits under environmental changes: Seasonal and daily mismatches produce temporal constraints

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Pollination is a key tenet of ecosystem sustainability and food security, but it is threatened by climate change. While many studies investigated the response of plant‐pollination traits to temperature, few attempted multifactorial and integrative approaches with ...
Mathieu A. J. Leclerc, Marc Gibernau, Sylvain Pincebourde   +2 more
wiley   +1 more source

Identification and Quantification of Volatile Organic Compounds and Bioaerosols in the Conservation Processes of Guanche Mummies

Archaeometry, EarlyView.
ABSTRACT The Guanche mummies, ancient inhabitants of the Canary Islands, represent a significant part of the historical heritage preserved at the Museum of Nature and Archaeology (MUNA) in Tenerife, Spain. These mummies, subjected to artificial conservation practices, are of great interest to conservators seeking to understand their mummification ...
Benigno Sánchez, Maria Cristina Canela, Maria Garcia Morales, Juan Gilaranz, Murilo de Oliveira Souza, Ruth Mª. Rufino García   +5 more
wiley   +1 more source

Solid Shampoo Is Mostly Not Preserved, in Contrast to Liquid Shampoos Used in Hairdressing—A Market Survey in Four European Countries

Contact Dermatitis, EarlyView.
Most solid shampoos (68.6%) did not contain preservatives according to Annex V of the EU Cosmetics Regulation (EC 1223/2009), while all liquid shampoos did. The number of preservatives used was significantly greater in liquid shampoos. ABSTRACT Background Hairdressers are frequently exposed to shampoos, both from neat liquid products and dilutions ...
Wolfgang Uter, Anders B. Funch, Mikkel Bak Jensen, Christoffer Kursawe Larsen, Ying X. Teo, Jeanne D. Johansen, Carola Lidén, Ian R. White   +7 more
wiley   +1 more source