Results 91 to 100 of about 26,898 (212)

Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract Our understanding of Alzheimer's disease (AD) and related dementias (ADRD) has grown exponentially, thanks to significant investments by the National Institute on Aging (NIA). This article celebrates the 40th anniversary of the NIA's Alzheimer's Disease Research Centers, highlighting the pivotal role of neuropathology as the bedrock for ...
D. Luke Fischer, Lea T. Grinberg, Jared T. Ahrendsen, Thomas G. Beach, Kevin F. Bieniek, Rudolph J. Castellani, Rati Chkheidze, Inma Cobos, Mark Cohen, John F. Crary, Dennis W. Dickson, Brittany N. Dugger, Sara R. Dunlop, Kurt Farrell, Bernardino Ghetti, Mohammad Haeri, William Harrison, Elizabeth Head, Annie Hiniker, Eric J. Huang, Anita Huttner, Pouya Jamshidi, Alifiya Kapasi, C. Dirk Keene, Julia Kofler, Caitlin S. Latimer, Ann C. McKee, Karin Mente, Michael B. Miller, Thomas J. Montine, Meaghan Morris, Melissa E. Murray, Peter T. Nelson, Kathy L. Newell, Richard J. Perrin, Biswarathan Ramani, R. Ross Reichard, Subhojit Roy, Johannes C. M. Schlachetzki, William W. Seeley, Geidy E. Serrano, Salvatore Spina, Andrew F. Teich, Shih‐Hsiu J. Wang, Thomas Wisniewski, Edward B. Lee   +45 more
wiley   +1 more source

Novel prion mutation (p.Tyr225Cys) in a Korean patient with atypical Creutzfeldt–Jakob disease

Clinical Interventions in Aging, 2019
Eva Bagyinszky,1,* YoungSoon Yang,2,* Vo Van Giau,1 Young Chul Youn,3 Seong Soo A An,1 SangYun Kim41Department of Bionano Technology, Gachon University, Sungnam, Korea; 2Department of Neurology, Veteran Health Service Medical Center, Seoul, Korea ...
Bagyinszky E, Yang Y, Giau VV, Youn YC, An SSA, Kim S   +5 more
doaj  

Dementia with Lewy bodies versus nonconvulsive status epilepticus in the diagnosis of a patient with cognitive dysfunction, complex visual hallucinations and periodic abnormal waves in EEG: a case report [PDF]

, 2014
BACKGROUND: The diagnosis of dementia with Lewy bodies (DLB) is often challenging in elderly individuals, not only for its various clinical features, sometimes, but also for its rare changes of periodic synchronous discharges (PSD) in ...
Feng na Chu, Jie Cao, Li Sun, Yudan Lv, Zan Wang   +4 more
core   +1 more source

Brain Atrophy and Leukoencephalopathy Following Tarlatamab: Case Report

Respirology Case Reports, Volume 13, Issue 10, October 2025.
We reported a case of rapid brain atrophy and leukoencephalopathy development after treatment with tarlatamab. Patients with brain metastases, regardless of treatment history, may be at increased risk of neurological events. Close monitoring and prompt management of adverse neurological events are warranted in such cases.
Kiriko Onishi, Toki Kitano, Yusuke Fujioka, Moeko Ota, Fumie Onishi, Kohei Miyake, Hisaaki Tanaka, Nobukazu Fujimoto   +7 more
wiley   +1 more source

CJD mimics and chameleons [PDF]

, 2017
Rapidly progressive dementia mimicking Creutzfeldt-Jakob disease (CJD) is a relatively rare presentation but a rewarding one to become familiar with, as the potential diagnoses range from the universally fatal to the completely reversible.
Mead, S, Rudge, P
core   +1 more source

Therapeutic Oligonucleotides for Neurodegenerative Diseases: Aptamer Strategies and Clay Nanoparticle‐Based Delivery

The Chemical Record, Volume 25, Issue 10, October 2025.
This review explores aptamers as therapeutic oligonucleotides targeting neurodegenerative diseases, including Alzheimer's, Parkinson's, and Huntington's, with a focus on G‐quadruplex‐forming sequences. It discusses chemical modifications that enhance aptamer stability and function, alongside the use of clay nanoparticles, such as halloysite nanotubes ...
Valentina Arciuolo, Federica D’Aria, Maria Rita Caruso, Martina Maria Calvino, Jussara Amato, Giuseppe Lazzara, Stefana Milioto, Concetta Giancola, Giuseppe Cavallaro, Bruno Pagano   +9 more
wiley   +1 more source

Coexistence of protease sensitive and resistant prion protein in 129VV homozygous sporadic Creutzfeldt–Jakob disease: a case report

Journal of Medical Case Reports, 2012
Introduction The coexistence of different molecular types of classical protease-resistant prion protein in the same individual have been described, however, the simultaneous finding of these with the recently described protease-sensitive variant or ...
Rodríguez-Martínez Ana B, de Munain Adolfo, Ferrer Isidro, Zarranz Juan J, Atarés Begoña, Villagra Nuria T, Arteagoitia Jose M, Garrido Joseba M, Juste Ramón A   +8 more
doaj   +1 more source

IVIG Delays Onset in a Mouse Model of Gerstmann-Sträussler-Scheinker Disease [PDF]

, 2019
Our previous studies showed that intravenous immunoglobulin (IVIG) contained anti-Aβ autoantibodies that might be able to treat Alzheimer's disease (AD).
Dodel, Richard, Du, Eileen, Du, Yansheng, Farlow, Martin R., Gu, Huiying, Kirchhein, Yvonne, Liu, Junyi, Mastrianni, James A., Peng, Hongjun, Zhao, Gang, Zhu, Timothy   +10 more
core   +1 more source

Update on Genetic Chorea

European Journal of Neurology, Volume 32, Issue 10, October 2025.
This review provides an updated clinical and genetic framework for the differential diagnosis of hereditary chorea. It guides neurologists through the interpretation of phenomenology, ancillary tests, and appropriate genetic techniques to achieve an accurate and timely diagnosis.
Jesús Pérez‐Pérez, Gonzalo Olmedo‐Saura, Saül Martínez‐Horta, Sara Bernal, Javier Pagonabarraga, Jaime Kulisevsky   +5 more
wiley   +1 more source

Severe, Persistent and Fatal Delirium in Psychogeriatric Patients Admitted to a Psychiatric Hospital

Dementia and Geriatric Cognitive Disorders Extra, 2015
Background/Aims: Although delirium is generally regarded as a transient syndrome, persistence of delirium in patients with cognitive impairment - even with fatal outcome - has been reported as well.
Ingrid S. Jans, Letty Oudewortel, Paulien M. Brandt, Willem A. van Gool   +3 more
doaj   +1 more source