Results 81 to 90 of about 26,898 (212)

Emerging infectious diseases: coping with uncertainty [PDF]

, 2009
The world’s scientific community must be in a state of constant readiness to address the threat posed by newly emerging infectious diseases. Whether the disease in question is SARS in humans or BSE in animals, scientists must be able to put into action ...
Cummings, L
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The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

Creutzfeldt-Jakob disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2013
Creutzfeldt⁃Jakob disease (CJD) is a degenerative central nervous system (CNS) disease caused by infection of prion protein (PrP), with clinical features including short course, rapid development and 100% mortality.
Lin WANG, Jian-rong LIU
doaj  

Stochastic Modelling Approach to the Incubation Time of Prionic Diseases

, 2003
Transmissible spongiform encephalopathies like the bovine spongiform encephalopathy (BSE) and the Creutzfeldt-Jakob disease (CJD) in humans are neurodegenerative diseases for which prions are the attributed pathogenic agents.
A. S. Ferreira, A. L. Horwich, B. J. West, D. J. Stekel, G. C. Telling, J. C. Cressoni, J. Collinge, J. D. Murray, J. S. Griffith, M. A. A. da Silva, M. Eigen, R. G. Will, R. M. Anderson, S. B. Prusiner, S. B. Prusiner, S. B. Prusiner   +15 more
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Does Improvement in Case Ascertainment Explain the Increase in Sporadic Creutzfeldt-Jakob Disease Since 1970 in the United Kingdom? [PDF]

, 2017
The aim of this study was to quantify the improvements in case ascertainment which are considered to explain the rise in the incidence of sporadic Creutzfeldt-Jakob disease.
Cohen, Carine H.
core  

Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains [PDF]

, 2015
Prions propagate as multiple strains in a wide variety of mammalian species. The detection of all such strains by a single ultrasensitive assay such as Real Time Quaking-induced Conversion (RT-QuIC) would facilitate prion disease diagnosis, surveillance ...
Caughey, Byron, Gambetti, Pierluigi, Ghetti, Bernardino, Groveman, Bradley R., Hughson, Andrew G., Nonno, Romolo, Orrú, Christina D., Raymond, Lynne D., Zou, Wenquan   +8 more
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Blood‐based Alzheimer's disease biomarkers in a behavioral neurology clinic: Real‐world implementation, clinical utility, and diagnostic performance

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION Blood‐based biomarkers (BBMs) for Alzheimer's disease (AD), including plasma phosphorylated tau (p‐tau), are increasingly used in clinical practice, but “real‐world” implementation patterns, context‐of‐use (COU), clinical utility, and diagnostic performance are incompletely understood. METHODS A retrospective analysis of the first
Igor Prufer Q C Araujo, Tara Ellingson, Nicholas U. Schwartz, Connor D. Dietz, Gautam Tammewar, Kaancan Deniz, Manizhe Eslami‐Amirabadi, Andrew G. Breithaupt, Marci Rosenberg, Nhat Minh Bui, Yasmeen Gonzalez, Renaud La Joie, Peter A. Ljubenkov, Katherine L. Possin, Julio C. Rojas, David N. Soleimani‐Meigooni, Yingbing Wang, Adam M. Staffaroni, Melanie L. Stephens, Elena Tsoy, Charles C. Windon, Adam L. Boxer, Gil D. Rabinovici, Bruce L. Miller, Lawren VandeVrede   +24 more
wiley   +1 more source

Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt-Jakob disease and rapid dementias:a longitudinal multicentre study over 10 years [PDF]

, 2012
To date, cerebrospinal fluid analysis, particularly protein 14-3-3 testing, presents an important approach in the identification of Creutzfeldt–Jakob disease cases.
Aguzzi, Adriano, Calero, Miguel, Gawinecka, Joanna, Green, Alison, Karch, Andre, Knight, Richard, Kulczycki, Jerzy, Ladogana, Anna, Laplanche, Jean-Louis, Mitrova, Eva, Peoc'h, Katell, Pocchiari, Maurizio, Saiz, Albert, Sanchez-Juan, Pascual, Sanchez-Valle, Raquel, Schelzke, Gabi, Sklaviadis, Theodor, Slivarichova, Dana, Stoeck, Katharina, van Duijn, Cornelia M., Zerr, Inga   +20 more
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Plasma p‐tau217, NfL, GFAP diagnostic performance and biomarker profiles in Alzheimer's disease, frontotemporal dementia, and psychiatric disorders, in a prospective unselected neuropsychiatry memory clinic

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Plasma biomarkers offer promise for improving the diagnosis of Alzheimer's disease (AD) and differentiating AD and other neurodegenerative disorders (NDs) like frontotemporal dementia (FTD) from primary psychiatric disorders (PPDs), particularly in younger patients.
Dhamidhu Eratne, Matthew Kang, Charles B Malpas, Christa Dang, Courtney Lewis, Oneil G Bhalala, Qiao‐Xin Li, Steven Collins, Colin L Masters, Samantha M Loi, Alexander F Santillo, Kaj Blennow, Henrik Zetterberg, Dennis Velakoulis, And The MiND Study Group   +14 more
wiley   +1 more source

Gerstmann-Sträussler-Scheinker disease subtypes efficiently transmit in bank voles as genuine prion diseases. [PDF]

, 2016
Gerstmann-Sträussler-Scheinker disease (GSS) is an inherited neurodegenerative disorder associated with mutations in the prion protein gene and accumulation of misfolded PrP with protease-resistant fragments (PrPres) of 6–8 ...
Agrimi, Umberto, Appleby, Brian S., Cohen, Mark L., Di Bari, Michele A., D’Agostino, Claudia, Gambetti, Pierluigi, Ghetti, Bernardino, Marcon, Stefano, Nonno, Romolo, Pirisinu, Laura, Poleggi, Anna, Riccardi, Geraldina   +11 more
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