Results 1 to 10 of about 22,461 (156)

Gut Microbiota Provide Co‐Existing Strategies for Two Species of Symmetrically Distributed Rodents in Competition for Food [PDF]

Ecology and Evolution
Gut microbiota provides an effective strategy for sympatric proximal species to coexist in interspecific competition. In the present study, 16S rRNA gene sequencing was used to investigate the gut microbial of the Cricetulus longicaudatus and Apodemus ...
Yue Ren, Mengfan Tao, Guangtong Guo, Kuiyou Chen, Xinsheng Pu, Yu Hou, Xin'gen Yang   +6 more
doaj   +3 more sources

Patatin-domain-containing (phospho)lipases under control: Mammalian co-regulators and pathogenic activation mechanisms. [PDF]

FEBS Open Bio
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Dubey N, Riegler-Berket L, Oberer M.
europepmc   +2 more sources

Bacterial Glutamine Synthetases as a Novel Metabolic Selection Marker to Improve CHO Cell Culture Performance Through Selection Stringency Modulation. [PDF]

Biotechnol J
Graphical Abstract and Lay Summary Metabolic selection markers have improved stable cell line generation by enhancing productivity without relying on antibiotics. This study evaluated bacterial glutamine synthetases as novel selection markers in CHO cells, identifying variants that significantly increased antibody titers and revealed structural ...
Heinzelmann D, Michelarakis N, Reuss F, Lindner B, Karow-Zwick AR, Bauer J, Renner B, Fischer S, Schulz P, Schmidt M.   +9 more
europepmc   +2 more sources

Tandem Repeat Diversity in Two Closely Related Hamster Species—The Chinese Hamster (Cricetulus griseus) and Striped Hamster (Cricetulus barabensis)

Biomedicines, 2022
The Chinese hamster (Cricetulus griseus) and striped hamster (Cricetulus barabensis) are very closely related species with similar karyotypes. The karyotypes differ from each other by one Robertsonian rearrangement and X-chromosome morphology.
Nadezhda G. Ivanova, Irina V. Kartavtseva, Vera N. Stefanova, Dmitrii I. Ostromyshenskii, Olga I. Podgornaya   +4 more
doaj   +3 more sources

Gut microbiota and quantitative traits divergence at different altitude of long-tailed dwarf hamsters, Cricetulus longicaudatus [PDF]

Frontiers in Microbiology
To investigate the community structure and diversity of gut microflora and their function in body mass regulation, as well as the effects of various locations on gut microbiota and Cricetulus longicaudatus body mass regulation at various elevations.
Yue Ren, Mengfan Tao, Xiaoliang Wang, Xinsheng Pu, Guangtong Guo, Kuiyou Chen, Bingyu Zhao, Yu Hou, Xin'gen Yang, Yumei Xu   +9 more
doaj   +2 more sources

Effects of dietary nutrients of the gut microbiota in the long‐tailed dwarf hamster (Cricetulus longicaudatus) [PDF]

Ecology and Evolution
Gut microbiota is a key factor in maintaining the dietary and metabolic homeostasis of small mammals. To explore the effect of diet on the gut microbiota of the long‐tailed dwarf hamster (Cricetulus longicaudatus), 16S rDNA high‐throughput sequencing ...
Kanglin Cao, Mengfan Tao, Xinsheng Pu, Yu Hou, Yue Ren, Wei Liu, Xin'gen Yang   +6 more
doaj   +2 more sources

Development of a single-nucleotide polymorphism panel genotyping system for genetic analysis of Chinese hamsters. [PDF]

Animal Model Exp Med
Here, we developed a novel Chinese hamster genetic quality detection system using single‐nucleotide polymorphism (SNP) markers following this process. To obtain SNP loci, we conducted whole genome sequencing on 24 Chinese hamsters. Then, we employed an SNP loci screening criterion that we set up previously and initially screened 214 SNP loci with wide ...
Sun M, Guo Y, Ren Z, Song A, Lu J, Li C, Lv J, Guo M, Liu X, Du X, Chen Z, Song G, He Y, Chen Z, Huo X.   +14 more
europepmc   +2 more sources

Proton First: Rationalizing a Proton Transfer in a Protein-Fragment Complex. [PDF]

ChemMedChem
We combine experimental and theoretical approaches to investigate benzoic acid binding to Protein Kinase A. The crystal structure shows benzoic acid protonated in the complex. Isothermal titration calorimetry (ITC) fails to detect binding, likely due to low affinity.
Vatheuer H, Paulus J, Johannknecht L, Keller G, Ziora RM, Stelzl LS, Czodrowski P.   +6 more
europepmc   +2 more sources

Cadmium exposure induces changes in gut microbial composition and metabolic function in long‐tailed dwarf hamsters, Cricetulus longicaudatus [PDF]

Ecology and Evolution
Numerous studies have demonstrated that exposure to cadmium disrupts the diversity and composition of the gut microbiota, resulting in damage to organ tissue.
Mengfan Tao, Kanglin Cao, Xinsheng Pu, Yu Hou, Lei He, Wei Liu, Yue Ren, Xin'gen Yang   +7 more
doaj   +2 more sources

Distribution and Host Selection of the Chigger Mite Leptotrombidium rupestre, a Potential Vector of Scrub Typhus, in Southwest China. [PDF]

Vet Med Sci
Based on field surveys in southwest China between 2001 and 2022, this paper retrospectively reports the distribution and host selection of L. rupestre in the region for the first time. A total of 4675 L. rupestre were identified from 28 species of small mammal hosts in 23 of 114 survey sites and it was mainly distributed in higher latitudes (31–33° N ...
Yu R, Guo XG, Lv Y, Yin PW, Song WY, Peng PY, Qian TJ, Xiang R, Chen YL, Li B.   +9 more
europepmc   +2 more sources