Results 21 to 30 of about 16,408 (183)

Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome. [PDF]

, 2013
Chinese hamster ovary (CHO) cells, first isolated in 1957, are the preferred production host for many therapeutic proteins. Although genetic heterogeneity among CHO cell lines has been well documented, a systematic, nucleotide-resolution characterization
Bian, Chao, Rosenbloom, Jeffrey, Nagarajan, Harish, Xu, Xun, George Yerganian, Deniz Baycin-Hizal, Bordbar, Aarash, Min Xie, Yerganian, George, Chao Bian, Betenbaugh, Michael, Chen, Wenbin, Förster, Jochen, Anne M Roth, Latif, Haythem, Harish Nagarajan, O'Brien, Edward, Aarash Bordbar, Yuxiang Li, Xie, Min, Baycin-Hizal, Deniz, Famili, Iman, Jeffrey Rosenbloom, Li, Ning, Xun Xu, Jochen Forster, Michael J Betenbaugh, Palsson, Bernhard O, Lewis, Nathan E., Nathan E Lewis, Wang, Jun, Lewis, Nathan E, Jun Wang, Edward O'Brien, Iman Famili, Bernhard O Palsson, Wenbin Chen, Haythem Latif, Li, Yuxiang, Ning Li, Roth, Anne M, Xin Liu, Liu, Xin, Roth, Anne M., Palsson, Bernhard O.   +44 more
core   +1 more source

PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz

eLife, 2017
Dephosphorylation of translation initiation factor 2 (eIF2α) terminates signalling in the mammalian integrated stress response (ISR) and has emerged as a promising target for modifying the course of protein misfolding diseases.
Ana Crespillo-Casado, Joseph E Chambers, Peter M Fischer, Stefan J Marciniak, David Ron   +4 more
doaj   +1 more source

Development of a single-nucleotide polymorphism panel genotyping system for genetic analysis of Chinese hamsters. [PDF]

Animal Model Exp Med
Here, we developed a novel Chinese hamster genetic quality detection system using single‐nucleotide polymorphism (SNP) markers following this process. To obtain SNP loci, we conducted whole genome sequencing on 24 Chinese hamsters. Then, we employed an SNP loci screening criterion that we set up previously and initially screened 214 SNP loci with wide ...
Sun M, Guo Y, Ren Z, Song A, Lu J, Li C, Lv J, Guo M, Liu X, Du X, Chen Z, Song G, He Y, Chen Z, Huo X.   +14 more
europepmc   +2 more sources

Fig 7, aBSREL Data Monkey Analysis Results for NAIP Protein

, 2022
Fig 7, aBSREL Data Monkey Analysis Results for NAIP Protein. Six Aligned DNA coding sequences were taken from the NAIP FASTA file with stop codons excluded.
Dylan Hart (12218678), Ryan Luedtke (12214127), Ean Chalfie (12236018)   +2 more
core   +1 more source

Found in translation: CHO cell microproteins are a new class of process-related impurity in mAb drug products

, 2021
A protein sequence database comprised of 56,478 Cricetulus griseus (taxon identifier 10029) proteins downloaded from UniProt in November 2021 (UniProt Consortium, 2021) and 5,645 novel proteoforms (derived from uORFs, ouORFs and ORFs encoded on NCBI ...
Colin Clarke
core   +1 more source

Figure 15.) Sliding Window Analysis. dN/dS ratios according to nucleotide position for cat, rodent and primate NAIP proteins.

, 2022
Figure 15.) Sliding Window Analysis. The dN/dS ratios according to nucleotide position for cat, rodent and primate NAIP proteins. Species used are Lynx canadensis, Felis catus, Rattus norvegicus, Cricetulus griseus, Pan Troglodytes, and Homo sapiens. One
Dylan Hart (12218678)
core   +1 more source

Functional and structural characterization of HspB1/Hsp27 from Chinese hamster ovary cells

FEBS Open Bio, 2019
Small heat shock proteins (sHsps) endow cells with stress tolerance. Of the various sHsps in mammals, HspB1, also known as Hsp27, is the most ubiquitous. To examine the structure and function of HspB1, we expressed, purified, and characterized HspB1 from
Eiryo Sha, Manami Nakamura, Kazuya Ankai, Yohei Y. Yamamoto, Toshihiko Oka, Masafumi Yohda   +5 more
doaj   +1 more source

Cricetulus barabensis

, 2018
Cricetulus barabensis (Pallas, 1773) —Striped Dwarf Hamster, Chinese striped hamster Mus barabensis Pallas, 1773 p.704; Type locality- Kasmalinskii Bor (village in Altai mountain), bank of Ob River, west Siberia, Russia.
Baccus, John T., Koprowski, John L., Jo, Yeong-Seok   +2 more
core   +1 more source

Figure 14.) Sliding Window Analysis. dN/dS ratios according to nucleotide position for cat, rodent and primate NLRC4 proteins.

, 2022
Figure 14.) Sliding Window Analysis. The dN/dS ratios according to nucleotide position for cat, rodent and primate NLRC4 proteins. Species used are Lynx canadensis, Felis catus, Rattus norvegicus, Cricetulus griseus, Pan Troglodytes, and Homo sapiens ...
Dylan Hart (12218678)
core   +1 more source

Cricetulus Milne-Edwards 1867

, 1993
<p> <i>Cricetulus</i> Milne-Edwards, 1867. Ann. Sci. Nat. (Paris), 7:376.</p> <p> TYPE SPECIES: <i>Cricetulus griseus</i> Milne-Edwards, 1867 (= <i>Mus barabensis</i> Pallas, 1773).</p> < ...
Guy G. Musser, Michael D. Carleton
core   +1 more source